ArticleProstate international2026
Clinicopathologic profile of Filipino men with low-risk prostate cancer and predictors of unfavorable pathology at radical prostatectomy.
Article in Prostate international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Active surveillance (AS) is the preferred initial management for low-risk prostate cancer; however, a substantial proportion of patients are found to harbor more advanced disease at radical prostatectomy. This study evaluated the clinicopathologic features and surgical outcomes of Filipino men with low-risk prostate cancer and identified predictors of unfavorable pathology. Materials and methods: This retrospective cohort study included 65 Filipino men with low-risk prostate cancer who underwent radical prostatectomy. Low-risk disease was defined as grade group 1 (Gleason score: 3 + 3 = 6) and prostate-specific antigen (PSA) < 10 ng/mL. Clinicopathologic features included age, PSA, biopsy characteristics, and measures of tumor volume such as the number of positive cores and percent positive cores (PPC). Unfavorable pathology was defined as upgrading to grade group ≥2 or grade group 1 with tertiary pattern 4, pathologic upstaging (pT3-pT4 or pN1), or both. Logistic regression and receiver operating characteristic analyses were performed to identify predictors of unfavorable pathology and determine an optimal cutoff for PPC. Results: Unfavorable pathology was observed in 56.92% of patients, predominantly due to upgrading, with fewer cases demonstrating upstaging. No cases of regional lymph node metastasis were identified. On multivariable analysis, PPC (per 10% increase) was a significant predictor of unfavorable pathology (odds ratio: 2.95, 95% confidence interval: 1.60-6.58; Conclusions: A substantial proportion of Filipino patients with low-risk prostate cancer harbor more advanced disease at radical prostatectomy. Tumor volume, as measured by PPC, may help identify patients at risk of unfavorable pathology and aid in refining selection of candidates for active surveillance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.