Evidence map›Paper›PMID 42801017›Full record

ArticleClinical case reports2026

Successful Management of Severe Hepatic Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation in a Child With β-Thalassemia Major: Clinical Lessons From Early Therapeutic Escalation.

Hind Alhiraki, Amal Ali Fares, Maged Kheder

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hind AlhirakiDepartment of Pediatrics Children's University Hospital, Faculty of Medicine, Damascus University Damascus Syria.ORCID https://orcid.org/0000-0003-1290-4616
Amal Ali FaresDepartment of Pediatrics Children's University Hospital, Faculty of Medicine, Damascus University Damascus Syria.ORCID https://orcid.org/0009-0007-0702-7483
Maged KhederPediatric Hematopoietic Stem Cell Transplantation Center, Head of National Stem Cell Center (HAYAT) Children's University Hospital, Faculty of Medicine, Damascus University Damascus Syria.ORCID https://orcid.org/0000-0003-3837-9549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe hepatic acute graft-versus-host disease can occur early after allogeneic hematopoietic stem cell transplantation without skin involvement, presenting with rapidly progressive cholestatic liver dysfunction. Early recognition and prompt escalation to multimodal immunosuppressive therapy achieve complete biochemical remission and durable hematopoietic recovery, highlighting the crucial role of early, multidisciplinary pediatric management.

Indexed as

acute graft‐versus‐host diseasehepatic‐predominant GVHDimmunosuppressive therapypediatric hematopoietic stem cell transplantationruxolitinibβ‐thalassemia major

Identifiers

PMID42801017
PMCPMC13615359

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.