ArticleBMC musculoskeletal disorders2026
Prognostic value of the "modified Osteoporotic Fracture score" for treatment decision in osteoporotic vertebral fractures.
Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe mOF score shows promise as a reliable tool to guide treatment decisions of osteoporotic vertebral fractures (OVFs). However, the prognostic value is lacking. This study aims to assess the prognostic value of the mOF score considering clinical and radiological outcomes in accordance with compliant or non-compliant management.
methodsA retrospective cohort study included all patients aged ≥50 years and diagnosed with acute thoracolumbar OVF between 2017 and 2021. Final treatment was compared with the recommendations according to the mOF score. Clinical and radiological outcome variables were pairwise compared in each group of treatment recommendation.
resultsFinal analysis included 482 patients. 81.95% received non-surgical management. Overall, the accuracy rate was 75.1%. The mOF score achieved a sensitivity of 24.7% and a specificity of 86.4% for surgical management prediction (AUC 0.55). In patients with surgical treatment recommendations, compliant management was associated with a significantly lower rate of fracture progression than non-compliant management (11% against 45%, p = 0.019), and lower decline in independent living status (0% compared with 10.6%, p = 0.311). In patients with non-surgical treatment recommendations, non-compliant management was associated with better results in radiological progression (p < 0.001), pain relief (p < 0.001), and the need for further therapy due to poor evolution (p = 0.088).
conclusionsThe mOF score demonstrated limited predictive capacity in discriminating the actual received treatment in our cohort. The surgical recommendation was meaningful, identifying better outcomes in patients compliant with the recommendation; for the non-surgical recommendations, vertebral augmentation still may provide a better outcome than conservative bracing and analgesics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.