ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Impact of SGA, AGA, and LGA birthweight subclassification on NICU mortality risk identification: a cohort study.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
objectiveTo assess whether subdividing small (SGA, <10th), appropriate (AGA, 10th-90th), and large (LGA, >90th percentile) for gestational age (GA) birthweight classifications improves mortality risk estimation among preterm infants in neonatal intensive care units (NICUs). STUDY
designData from 25,779 singleton inborn NICU infants (24-30 weeks GA) from the Pediatrix Clinical Data Warehouse (2013-2018) were analyzed. Infant birthweights were subclassified into 12 subgroups (extremely SGA [eSGA], <3rd; moderately SGA [mSGA], 3rd-<10th, 8 AGA categories [3-AGA to 9-AGA]; mLGA, >90th-97th; eLGA, >97th percentile). Mortality probability by birthweight category was modeled using logistic regression.
resultMortality probability was higher for infants classified as eSGA (28.9%, 95% CI [26.4-31.4%]) than mSGA (9.9% [8.7-11.3%]). Smaller AGA infants had higher mortality than larger AGA infants (e.g., 3-AGA: 8.5% [7.5-9.7%] vs. 9-AGA: 5.0% [4.2-5.9%]). Subdividing LGA provided no additional information.
conclusionSubdivision of SGA and AGA birthweight categories may improve mortality risk prediction among premature infants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.