Evidence map›Paper›PMID 42800796›Full record

ArticleCommunications biology2026

Unexpected functional role of the transactivation domain for nuclear import of STAT5.

Sabrina Ernst, Merith Borgen-Möller, Andrea Küster, Henning Schurse, Gerhard Müller-Newen

Abstract read
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sabrina ErnstConfocal Microscopy Facility, Interdisciplinary Center for Clinical Research IZKF, Uniklinik RWTH Aachen, Aachen, Germany.
Merith Borgen-MöllerInstitute of Biochemistry and Molecular Biology, Uniklinik RWTH Aachen, Aachen, Germany.
Andrea KüsterInstitute of Biochemistry and Molecular Biology, Uniklinik RWTH Aachen, Aachen, Germany.
Henning SchurseInstitute of Biochemistry and Molecular Biology, Uniklinik RWTH Aachen, Aachen, Germany.
Gerhard Müller-NewenInstitute of Biochemistry and Molecular Biology, Uniklinik RWTH Aachen, Aachen, Germany. mueller-newen@rwth-aachen.de.ORCID 0000-0002-0820-7693

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 417911533
6 · The paper itself

Abstract

Signal transducer and activator of transcription 5 (STAT5) is a key transcriptional regulator acting downstream of hematopoietic cytokines and hormones, such as erythropoietin (Epo), thrombopoietin or prolactin. STAT5-mediated gene regulation involves tyrosine phosphorylation at cytokine receptors and subsequent nuclear import. We studied STAT5 nucleocytoplasmic shuttling via live-cell imaging of fluorescent mutants in STAT5

Indexed as

Cell NucleusSTAT5 Transcription FactorTranscriptional ActivationActive Transport, Cell NucleusHeLa CellsHumansPhosphorylationProtein DomainsSTAT5 Transcription Factor

Identifiers

PMID42800796
PMCPMC13615974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.