Evidence map›Paper›PMID 42799979›Full record

ArticleBulletin of experimental biology and medicine2026

Generation of Vascular Organoids from Human iPSCs to Study Neurodegenerative Processes.

D A Lifanov, E S Perepelitsa, A A Kopylova, A V Blagova, K O Salina, A Satish, S O Yurchenko, A B Salmina, S N Illarioshkin

Abstract read
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Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

D A LifanovRussian Center of Neurology and Neurosciences, Moscow, Russia. DMTLiFNV@gmail.com.
E S PerepelitsaRussian Center of Neurology and Neurosciences, Moscow, Russia.
A A KopylovaBauman Moscow State Technical University, Moscow, Russia.
A V BlagovaRussian Center of Neurology and Neurosciences, Moscow, Russia.
K O SalinaBauman Moscow State Technical University, Moscow, Russia.
A SatishRussian Center of Neurology and Neurosciences, Moscow, Russia.
S O YurchenkoBauman Moscow State Technical University, Moscow, Russia.
A B SalminaRussian Center of Neurology and Neurosciences, Moscow, Russia.
S N IllarioshkinRussian Center of Neurology and Neurosciences, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organoids are a type of three-dimensional cellular constructs comprising cells of various specializations (phenotypes). In contrast to simple cellular spheroids (aggregates), cells within organoids exhibit more complex differentiation and functional characteristics. This study describes a protocol for generating vascular organoids incorporating vascular endothelial cells. A step-by-step workflow is presented, detailing the necessary reagents and consumables. Additionally, a method for validating differentiation outcomes using immunofluorescence staining is described. Morphological differences are reported between organoids derived from stem cells of a healthy donor and those from patients with Alzheimer's or Parkinson's disease.

Indexed as

Induced Pluripotent Stem CellsOrganoidsAlzheimer DiseaseCell Culture TechniquesCell DifferentiationEndothelial CellsHumansParkinson Diseasecell culturecytologyneurodegenerative diseasesneurologyorganoids

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.