ArticleClinical oral investigations2026
Influence of cold plasma activation on fluoride uptake and demineralization of enamel.
Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
objectivesThis in vitro study investigated the influence of cold plasma activation time prior to 1.25% fluoride gel application on fluoride uptake and demineralization of enamel. MATERIALS AND
methodsHuman enamel specimens (n = 200) were either treated with a dielectric-barrier plasma discharge at a constant distance (d = 1 mm), pulse repetition frequency (f
resultsFluoride gel significantly increased KOH-soluble and structurally bound fluoride and reduced calcium and phosphate release. Cold plasma activation had no significant effect on fluoride uptake or calcium and phosphate release. Plasma activation for 2 and 30 s resulted in a significant reduction of the calcium/phosphate ratio compared to the groups without plasma activation and without fluoride gel (p
conclusionsSingle cold plasma activation prior to fluoride gel application did not improve fluoride uptake or reduce demineralization of enamel. CLINICAL RELEVANCE: Under the investigated conditions, additional cold plasma activation provided no benefit beyond conventional topical fluoride treatment.
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