Evidence map›Paper›PMID 42799920›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Low handgrip strength in advanced cancer: associated factors and clinical implications in palliative care.

Larissa Pereira Santos, Bianca Sakamoto Ribeiro Paiva, Karla Santos Da Costa Rosa, Carlos Eduardo Paiva, Livia Costa De Oliveira

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Larissa Pereira SantosGPQual-Palliative Care and Quality of Life Research Group, Barretos Cancer Hospital, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-9419-0946
Bianca Sakamoto Ribeiro PaivaGPQual-Palliative Care and Quality of Life Research Group, Barretos Cancer Hospital, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-2711-8346
Karla Santos Da Costa RosaGPQual-Palliative Care and Quality of Life Research Group, Barretos Cancer Hospital, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0951-8725
Carlos Eduardo PaivaGPQual-Palliative Care and Quality of Life Research Group, Barretos Cancer Hospital, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7934-1451
Livia Costa De OliveiraGPQual-Palliative Care and Quality of Life Research Group, Barretos Cancer Hospital, São Paulo, Brazil. livia.oliveira@inca.gov.br.ORCID http://orcid.org/0000-0002-5052-1846

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHandgrip strength (HGS) is a widely used clinical and prognostic tool in oncology and is associated with several outcomes in palliative care (PC).

objectiveTo evaluate the factors associated with low HGS in patients with advanced cancer receiving PC.

methodsA cross-sectional study was conducted at the Brazilian National Cancer Institute between 2023 and 2025, including patients with advanced cancer receiving PC. HGS was measured using a Jamar® hydraulic dynamometer. HGS values below the first tertile were classified as low HGS. Clinical, sociodemographic, functional, and nutritional data were collected. Analyses, stratified by sex, included logistic regression, with odds ratios (ORs) and 95% confidence intervals (CI) as estimators.

resultsFive hundred twenty-seven patients were included, with a median age of 66 years, predominantly women (58%), and with primary tumor sites in the gastrointestinal tract (24%) and gynecological (21%). The cutoff points defining low HGS (1

conclusionAdvanced age and lower KPS were independently associated with low HGS in patients with advanced cancer receiving palliative care. These findings support HGS as an objective indicator of physical vulnerability in this population.

Indexed as

Hand StrengthNeoplasmsPalliative CareAgedAged, 80 and overAge FactorsBrazilCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedPrognosisRisk FactorsSex FactorsAdvanced cancerAssociated factors in functional capacityHandgrip strengthPalliative care

Identifiers

PMID42799920
PMCPMC13615993

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.