ArticleBioresources and bioprocessing2026
Continuous autotrophic production of alcohols with Clostridium autoethanogenum LAbrini in a submerged membrane bioreactor.
Article in Bioresources and bioprocessing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Due to the generally low growth rates of acetogens, conventional batch and continuously operated syngas fermentation processes in suspension cultures, e.g., stirred tank bioreactors, typically result in low cell concentrations and, thus, limited volumetric productivities (space-time yields). To increase cell concentrations in syngas fermentations, a continuously operated submerged microfiltration membrane bioreactor (MBR) was applied on a L-scale with C. autoethanogenum LAbrini for the production of alcohols. Cell retention was achieved by inserting a sintered metal microfiltration rod into a standard stirred-tank bioreactor. A batch phase followed by continuous operation with full cell retention until 95% CO conversion was used to start the MBR operation with partial cell retention. Three continuous syngas fermentation processes were operated until a quasi-steady state was achieved with total process times of up to 10 days. Higher cell (4.4 g L
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