Evidence map›Paper›PMID 42799786›Full record

ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2026

Cross-species incompatibilities offer new insights into the functional consequences of satellite DNA evolution.

Amber M Ridgway, Piero Lamelza, Michael A Lampson, Mia T Levine

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amber M RidgwayDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA.
Piero LamelzaDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA.
Michael A LampsonDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA. lampson@sas.upenn.edu.
Mia T LevineDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA. m.levine@sas.upenn.edu.ORCID https://orcid.org/0000-0003-4311-7535

Funding

Cell Biological mechanisms of centromere driveR35GM122475 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Michael Lampson · 2017 to 2026
$4.5M
Causes and functional consequences of chromatin evolutionR35GM124684 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Mia Tauna Levine · 2017 to 2026
$3.5M
The functional consequences of DNA repeat evolution in the early mammalian embryoR01HD120404 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Lampson, Mia Tauna Levine · 2026 to 2026
$600k
Eunice Kennedy Shriver National Institute of Child Health and Human Development HD120404National institute of general medicine GM122475National institute of general medicine GM124684NICHD NIH HHS R01 HD120404NIGMS NIH HHS R35 GM122475NIGMS NIH HHS R35 GM124684
6 · The paper itself

Abstract

Tandemly repeated, non-coding satellite DNAs are among the most rapidly evolving genetic elements in eukaryotic genomes, changing in identity, copy number, and genomic distribution. A growing list of empirical studies suggests that this rapid evolution has profound consequences on core biological processes. Here, we review recent studies that investigate the satellite DNA-mediated biology revealed by generating either inter-species hybrids or genotypes expressing divergent, satellite DNA-interacting proteins from a closely related species. The genetic incompatibilities that arise implicate chromosome segregation, DNA repair, the establishment of silent heterochromatin, and the spatial organization of chromosomes as essential processes vulnerable to the rapid evolution of satellite DNA. We discuss emergent themes from this relatively young body of literature and future challenges for the field.

Indexed as

DNA, SatelliteEvolution, MolecularAnimalsChromosome SegregationDNA RepairHeterochromatinHumansDNA, SatelliteHeterochromatinChromosome segregationDNA repairGenetic incompatibilityHeterochromatinRapid evolutionSatellite DNA

Identifiers

PMID42799786
PMCPMC13615996

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.