Evidence map›Paper›PMID 42799282›Full record

ArticleJournal of Indian Association of Pediatric Surgeons

Imaging-based Stratification and Management of Pediatric Liver Abscess with Rupture: Experience from a Tertiary Care Center.

Rishabh Patel, Palak Paliwal, Shalu Shah, Bhanu Khokhar, Atul Kumar Meena, Tanmay Anand, Pinaki Ranjan Debnath

Abstract read
In one paragraph

Article in Journal of Indian Association of Pediatric Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rishabh PatelDepartment of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and RML Hospital, New Delhi, India.
Palak PaliwalDepartment of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and RML Hospital, New Delhi, India.
Shalu ShahDepartment of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and RML Hospital, New Delhi, India.
Bhanu KhokharDepartment of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and RML Hospital, New Delhi, India.
Atul Kumar MeenaDepartment of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and RML Hospital, New Delhi, India.
Tanmay AnandDepartment of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and RML Hospital, New Delhi, India.
Pinaki Ranjan DebnathDepartment of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and RML Hospital, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Liver abscess in the pediatric age group is an uncommon but serious condition. Extension or rupture of a liver abscess may result in intrathoracic or intra-abdominal contamination and has traditionally been considered an indication for surgical intervention. With advances in imaging, antibiotics, and minimally invasive techniques, management strategies have evolved toward selective nonoperative approaches. Aim: This study aims to evaluate clinical presentation, radiological patterns, management strategies, and outcomes of pediatric liver abscess with true rupture, using imaging-based anatomical stratification. Materials and Methods: This prospective observational study was conducted between August 2022 and August 2024 at a tertiary care pediatric surgery unit. Children with radiologically confirmed liver abscesses demonstrating either contained extension or true rupture were included. Contrast-enhanced computed tomography was used to classify patients based on capsular integrity and extent of spillage. Management strategies included antibiotics, selective image-guided drainage, and surgery for strict indications. Nutritional status and serum albumin levels were assessed at admission and during follow-up. Results: A total of 94 children out of 349 patients with liver abscess extension or rupture were included. Contained subcapsular extension beneath an intact liver capsule constituted 52% of cases and was successfully managed with intravenous antibiotics alone. True rupture, defined by capsular breach with free spillage, accounted for the remaining cases, including thoracic rupture (18%), subdiaphragmatic rupture (16%), and free intraperitoneal rupture (14%). Minimally invasive drainage was required selectively. An exploratory laparotomy was performed in 2 children (2.1%) who developed generalized peritonitis. No mortality was observed. Conclusion: Contained subcapsular extension of pediatric liver abscess can be safely managed conservatively. Rupture requires careful imaging-based stratification, selective minimally invasive drainage, and timely surgical intervention when indicated. Surgery remains essential in children with generalized peritonitis or failed nonoperative management.

Indexed as

Albumin infusionconservative treatmentnutritional rehabilitationpediatric liver abscessruptured liver abscess

Identifiers

PMID42799282
PMCPMC13614804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.