Evidence map›Paper›PMID 42799168›Full record

ReviewHealth science reports2026

Financing of Human Papillomavirus Vaccination in Africa: A Scoping Review.

Kafayat Aminu, Jimoh Amzat, Rita Amarachi Nwebo, Precious Chika Nnannah, Chiamaka Norah Ezeagu, Aboyowa Arayuwa Edukugho, Olubukola Omobowale, Abba Shehu, Yovanthi Anurangi Jayasinghe, Ganiyat Amzat and 1 more

Abstract readReview
In one paragraph

Review in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kafayat AminuCentre for Evidence Synthesis and Implementation Research Cephas Health Research Initiative Inc Ibadan Nigeria.ORCID https://orcid.org/0000-0001-7438-2556
Jimoh AmzatDepartment of Sociology Usmanu Danfodiyo University Sokoto Nigeria.ORCID https://orcid.org/0000-0001-9564-1190
Rita Amarachi NweboCentre for Digital Health Research Innovation and Practice, Cephas Health Research Initiative Inc Ibadan Nigeria.ORCID https://orcid.org/0009-0009-3123-2596
Precious Chika NnannahCentre for Digital Health Research Innovation and Practice, Cephas Health Research Initiative Inc Ibadan Nigeria.ORCID https://orcid.org/0009-0000-3633-1395
Chiamaka Norah EzeaguCentre for Evidence Synthesis and Implementation Research Cephas Health Research Initiative Inc Ibadan Nigeria.
Aboyowa Arayuwa EdukughoThe African Field Epidemiology Network Nigeria Country Office Abuja Nigeria.
Olubukola OmobowaleDepartment of Community Medicine University of Ibadan Ibadan Nigeria.ORCID https://orcid.org/0000-0001-6795-6371
Abba ShehuThe African Field Epidemiology Network Nigeria Country Office Abuja Nigeria.ORCID https://orcid.org/0000-0002-8237-1344
Yovanthi Anurangi JayasingheCentre for Evidence Synthesis and Implementation Research Cephas Health Research Initiative Inc Ibadan Nigeria.ORCID https://orcid.org/0000-0001-5144-5550
Ganiyat AmzatDepartment of Economics Usmanu Danfodiyo University Sokoto Nigeria.
Kehinde Kazeem KanmodiDepartment of Research and Innovation University of Technology and Entrepreneurship Phnom Penh Cambodia.ORCID https://orcid.org/0000-0001-9906-3826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Human papillomavirus (HPV) vaccination is a critical intervention for cervical cancer prevention in Africa; however, program uptake and scale-up remain limited due to financing constraints. This scoping review mapped existing evidence on HPV vaccine financing in Africa, identifying prevailing funding mechanisms, cost estimates, delivery strategies, and challenges and opportunities for sustainable financing. Methods: Guided by the Arksey and O'Malley framework and PRISMA-ScR guidelines, we systematically searched nine electronic databases for peer-reviewed studies. Retrieved records were deduplicated and screened against eligibility criteria. Eligible studies underwent data extraction, followed by collation, summarization, and thematic synthesis. All costs were standardized to United States (US) Dollars and further adjusted to a common reference year (2025US) using the US Consumer Price Index (CPI-U) to enable comparison across study years. Results: Twenty-seven peer-reviewed studies were included. The review found heavy dependence on donor support, particularly from Gavi, with limited domestic co-financing across most countries. Per-dose costs ranged from US$0.27-US$19.76 (financial) and US$1.31-US$45.00 (economic) as reported, or US$0.32-US$26.50 and US$1.63-US$60.36 after adjustment to 2025 US; per fully immunized girl, costs ranged from US$6.68-US$40.03 and US$17.31-US$91.19 as reported, or US$8.31-US$53.69 and US$21.53-US$122.31 adjusted. Primary cost drivers included service delivery, personnel, and outreach to out-of-school girls. School-based delivery was more cost-effective in several contexts, and the single-dose schedule consistently showed lower cost with comparable efficacy, enhancing cost-effectiveness and reducing programmatic burden. Willingness to pay exists among private individuals, but out-of-pocket models remain inequitable. Conclusion: Donor funds, mainly Gavi, still drive HPV vaccination in most of Africa. The single-dose schedule cuts costs and logistics while remaining effective. For equitable, sustainable access, African countries must prioritize cost-effective vaccines, boost domestic funding, strengthen health systems, and adopt models that lessen reliance on external support.

Indexed as

Africafinancinghuman papillomavirusreviewvaccination

Identifiers

PMID42799168
PMCPMC13614079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.