Evidence map›Paper›PMID 42799070›Full record

ArticleACS omega2026

Intracellular Singlet Oxygen Generation Mediated by Upconversion Nanoparticles in RAW 264.7 Macrophages.

Amanda Annunciação Farhat, Bernardina Amorín Uscata, Magnus Ake Gidlund, Hiro Goto, Marisa Helena Gennari de Medeiros, Hermi Felinto Brito, Paolo Di Mascio

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amanda Annunciação FarhatDepartamento de Química, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo BR-05508-000, Brasil.ORCID https://orcid.org/0000-0002-6145-188X
Bernardina Amorín UscataInstituto de Medicina Tropical de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo BR- 05403-000, Brasil.ORCID https://orcid.org/0000-0002-4140-5915
Magnus Ake GidlundInstituto de Ciências Biológicas, Universidade de São Paulo, São Paulo, São Paulo BR-05508-000, Brasil.ORCID https://orcid.org/0000-0003-2047-1136
Hiro GotoInstituto de Medicina Tropical de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo BR- 05403-000, Brasil.
Marisa Helena Gennari de MedeirosDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo BR-05508-000, Brasil.ORCID https://orcid.org/0000-0002-5438-1174
Hermi Felinto BritoDepartamento de Química, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo BR-05508-000, Brasil.ORCID https://orcid.org/0000-0002-9876-4441
Paolo Di MascioDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo BR-05508-000, Brasil.ORCID https://orcid.org/0000-0003-4125-8350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upconversion nanoparticles (UCNPs) capable of generating reactive oxygen species under near-infrared (NIR) excitation have emerged as promising platforms for biomedical applications, particularly photodynamic therapy and immune-related modulation. Here, we investigate the biological application of core-shell UCNPs functionalized with a photosensitizer for the intracellular generation of singlet oxygen (

Identifiers

PMID42799070
PMCPMC13613876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.