Evidence map›Paper›PMID 42799003›Full record

ArticleACS omega2026

Identification of the Acetamide-Chalcone Derivative That Selectively Inhibits ABCG2 Transport Activity.

Arthur Henrique Gomes de Oliveira, Eli Silveira Alves Ducas, Thales Kronenberger, Jean Carlos Pereira Sousa, Bruna Estelita Ruginsk, Katalin Goda, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Vivian Rotuno Moure, Pablo José Gonçalves and 1 more

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Arthur Henrique Gomes de OliveiraGraduate Program in Pharmaceutical Sciences, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, Paraná 80210-170, Brazil.
Eli Silveira Alves DucasInstitute of Chemistry, Federal University of Goiás, Goiânia, Goiás 74001-970, Brazil.ORCID https://orcid.org/0000-0002-8117-3127
Thales KronenbergerInterfaculty Institute of Microbiology and Infection Medicine (IMIT), DZIF Tübingen Partner Site, University Hospital Tübingen, Tuebingen 72076, Germany.ORCID https://orcid.org/0000-0001-6933-7590
Jean Carlos Pereira SousaFaculty of Pharmacy, Federal University of Goiás, Goiânia, Goiás 74605-170, Brazil.
Bruna Estelita RuginskGraduate Program in Cell and Molecular Biology, Federal University of Parana, Curitiba, Paraná 80210-170, Brazil.
Katalin GodaDepartment of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Egytem tér 1, Debrecen H-4032, Hungary.
Fabiane Gomes de Moraes RegoGraduate Program in Pharmaceutical Sciences, Federal University of Parana, Curitiba, Paraná 80210-170, Brazil.
Geraldo PichethGraduate Program in Pharmaceutical Sciences, Federal University of Parana, Curitiba, Paraná 80210-170, Brazil.
Vivian Rotuno MoureGraduate Program in Pharmaceutical Sciences, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, Paraná 80210-170, Brazil.ORCID https://orcid.org/0000-0003-0968-8190
Pablo José GonçalvesInstitute of Chemistry, Federal University of Goiás, Goiânia, Goiás 74001-970, Brazil.ORCID https://orcid.org/0000-0003-0246-1073
Glaucio ValdameriGraduate Program in Pharmaceutical Sciences, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, Paraná 80210-170, Brazil.ORCID https://orcid.org/0000-0003-1882-1512

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug resistance (MDR) remains a major obstacle to effective cancer chemotherapy, often driven by the overexpression of ABC transporters such as ABCG2. In this study, we identified the synthetic chalcone derivative,

Identifiers

PMID42799003
PMCPMC13613470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.