ArticleJCEM case reports2026
Primary synovial sarcoma of the thyroid mimicking medullary thyroid cancer.
Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The differential diagnosis of a rapidly enlarging thyroid mass includes poorly differentiated thyroid carcinoma, anaplastic carcinoma, medullary thyroid carcinoma (MTC), lymphoma, and metastatic disease. Although fine-needle aspiration (FNA) provides important diagnostic clues, it may not be definitive. We report a 43-year-old woman with a long-standing goiter that enlarged rapidly over 6 months. FNA suggested MTC; however, serum calcitonin and carcinoembryonic antigen levels were within normal limits, creating clinicobiochemical discordance. Given this discrepancy, further evaluation was undertaken. Core needle biopsy of the thyroid mass demonstrated a spindle cell neoplasm, and immunohistochemistry supported a diagnosis of primary synovial sarcoma. Gallium-68-labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-octreotate positron emission tomography-computed tomography revealed distant metastases involving the lungs, bones, and bone marrow. In view of advanced disease with vascular encasement and metastatic spread, neoadjuvant chemotherapy was initiated. This case highlights the importance of histopathologic confirmation in atypical presentations of thyroid malignancy and underscores the limitations of cytology in rare spindle cell tumors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.