Evidence map›Paper›PMID 42798839›Full record

ArticleOncology letters2026

Identification and assessment of

Anette Roxana Gastelum-Quiroz, Noemí García-Magallanes, Andrea Ross-Orozco, Marco Alvarez-Arrazola, Fred Luque-Ortega, Karla Lizbeth Morales-Hernández, Dora Cedano-Prieto, Vanessa G Félix, Eliakym Arámbula-Meraz

Abstract read
In one paragraph

Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anette Roxana Gastelum-QuirozDepartment of Postgraduate Biomedical Sciences, Faculty of Chemical-Biological Sciences, Autonomous University of Sinaloa, 80010 Culiacán, Sinaloa, México.
Noemí García-MagallanesLaboratory of Biomedicine and Molecular Biology, Department of Biotechnology Engineering, Polytechnic University of Sinaloa, 82199 Mazatlán, Sinaloa, México.
Andrea Ross-OrozcoDepartment of Postgraduate Biomedical Sciences, Faculty of Chemical-Biological Sciences, Autonomous University of Sinaloa, 80010 Culiacán, Sinaloa, México.
Marco Alvarez-ArrazolaLaboratory of Biomedicine and Molecular Biology, Department of Biotechnology Engineering, Polytechnic University of Sinaloa, 82199 Mazatlán, Sinaloa, México.
Fred Luque-OrtegaBasic Sciences Laboratory, Faculty of Dentistry, Autonomous University of Sinaloa, 80010 Culiacán, Sinaloa, México.
Karla Lizbeth Morales-HernándezDepartment of Postgraduate Biomedical Sciences, Faculty of Chemical-Biological Sciences, Autonomous University of Sinaloa, 80010 Culiacán, Sinaloa, México.
Dora Cedano-PrietoLaboratory of Genetics and Molecular Biology, Faculty of Chemical and Biological Sciences, Autonomous University of Sinaloa, 80010 Culiacan, Sinaloa, México.
Vanessa G FélixAcademic Unit of Information Technology and Digital Innovation, Polytechnic University of Sinaloa, 82199 Mazatlán, Sinaloa, México.
Eliakym Arámbula-MerazDepartment of Postgraduate Biomedical Sciences, Faculty of Chemical-Biological Sciences, Autonomous University of Sinaloa, 80010 Culiacán, Sinaloa, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary thyroid carcinoma (PTC) is the most common type of endocrine malignancy worldwide. Although the prognosis of PTC is generally favorable, understanding its molecular mechanisms is of great importance for improving diagnostic stratification and clinical management. The present study aimed to identify genes that are consistently differentially expressed in PTC through an integrative analysis of transcriptomic datasets combined with experimental validation. Differential expression analysis of six RNA-sequencing datasets comparing PTC and adjacent non-tumor tissue identified 131 commonly dysregulated genes, including 128 upregulated and 3 downregulated genes. Functional enrichment and Kyoto Encyclopedia of Genes and Genomes analyses revealed that the aforementioned differentially expressed genes were significantly associated with 'tissue development', 'cell adhesion' and 'plasma membrane organization'. Additionally, protein-protein interaction network and centrality analyses identified fibronectin 1 (

Indexed as

gene expressionpapillary thyroid cancerRNA-sequencingtranscriptomic profiling

Identifiers

PMID42798839
PMCPMC13613191

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.