Evidence map›Paper›PMID 42798738›Full record

ArticleNeurobiology of language (Cambridge, Mass.)2026

Neural and Behavioral Predictors of Speech Motor Sequence Learning in Primary Progressive Aphasia.

Hilary E Miller, Michael Brickhouse, Daisy Hochberg, Alfonso Nieto-Castanon, Jason Tourville, Bradford C Dickerson, Frank H Guenther

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of language (Cambridge, Mass.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hilary E MillerDepartment of Speech, Language & Hearing Sciences, Boston University, Boston, MA, USA.ORCID https://orcid.org/0000-0002-0244-7119
Michael BrickhouseFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Charlestown, MA, USA.
Daisy HochbergFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Charlestown, MA, USA.
Alfonso Nieto-CastanonDepartment of Speech, Language & Hearing Sciences, Boston University, Boston, MA, USA.ORCID https://orcid.org/0000-0002-3451-3475
Jason TourvilleDepartment of Speech, Language & Hearing Sciences, Boston University, Boston, MA, USA.ORCID https://orcid.org/0000-0002-7197-2427
Bradford C DickersonFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Charlestown, MA, USA.ORCID https://orcid.org/0000-0002-5958-3445
Frank H GuentherDepartment of Speech, Language & Hearing Sciences, Boston University, Boston, MA, USA.ORCID https://orcid.org/0000-0002-1418-8580

Funding

Sequencing and Initiation in Speech ProductionR01DC007683 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI FRANK H GUENTHER · 2006 to 2026
$9.0M
Imaging tau, amyloid, and neurodegeneration in PPAR01DC014296 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI DICKERSON, BRADFORD C, JOHNSON, KEITH A. · 2016 to 2020
$4.3M
Toward Personalized Prognosis and Outcomes in Primary Progressive AphasiaR01NS131395 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BRADFORD C DICKERSON · 2026 to 2026
$824k
Predictors of Speech Motor Sequence Learning in Neurological DisordersF31DC020352 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MILLER, HILARY ELIZABETH · 2022 to 2024
$138k
NIDCD NIH HHS F31 DC020352NIDCD NIH HHS R01 DC007683NIDCD NIH HHS R01 DC014296NINDS NIH HHS R01 NS131395
6 · The paper itself

Abstract

This study investigated the clinical and neural correlates of speech motor sequence learning in primary progressive aphasia (PPA) to test specific predictions regarding the roles of the left posterior inferior frontal sulcus (pIFS) and left ventral premotor cortex (vPMC). A cohort of 26 participants with PPA completed a 2-day non-native consonant cluster learning paradigm. Participants also completed a battery of clinical speech-language assessments, including tests of phonological and motor programming ability, and T1-weighted structural MRI scans were obtained for a subcohort (

Indexed as

cortical thicknessGradient Order Directions Into Velocities of Articulators (GODIVA) modelprimary progressive aphasia (PPA)speech motor sequence learning

Identifiers

PMID42798738
PMCPMC13612843

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.