ArticleResearch in heart yield and translational medicine2025
Exploring the Impact of Fragmented QRS on Ejection Fraction and Other Echocardiographic Parameters in Systemic Sclerosis Patients: A Retrospective Cohort Study.
Article in Research in heart yield and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highlights: FQRS has no significant effect on EF and other echocardiographic parameters over at least a three-year interval in SSc patients. Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disorder that leads to fibrosis of the skin and internal organs. Fragmented QRS (fQRS) is an important electrocardiographic (ECG) finding related to myocardial fibrosis. This study aimed to evaluate the effect of fQRS on ejection fraction (EF) and other echocardiographic parameters in individuals diagnosed with SSc. Methods: This was a retrospective cohort study consisting of 52 patients with fQRS as the case group and 60 patients without fQRS as the control group. The characteristics and echocardiographic parameters of the patients from a minimum of a 3-year interval were recorded. All data were compared between the two groups using SPSS software, version 20.0 (IBM Corp). Results: There were no significant differences in demographics, paraclinical results, and echocardiographic parameters, including average EF, pulmonary hypertension, and tricuspid regurgitation velocity, between cases and controls at the beginning and end of the follow-up. Conclusion: Based on our results, fQRS had no significant effect on EF and other echocardiographic parameters over at least a 3-year interval in SSc patients. However, additional research with longer follow-up periods and larger sample sizes is needed to characterize the association fully.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.