Evidence map›Paper›PMID 42798657›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Changzhi Huang, Nanyi Xu, Lei Zhang, Kaiyuan Zheng, Wenrong Zhang, Shiqin Zhuo, Junli Li, Xiaoyong Wang, Shuqiang Lu, Jiuzao Lin

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Changzhi Huang *Department of Joint Surgery and Sports Medicine, Ningde Municipal Hospital, Ningde, Fujian, China.
Nanyi Xu *Ningde Clinical Medical College of Fujian Medical University, Ningde, Fujian, China.
Lei Zhang *Ningde Clinical Medical College of Fujian Medical University, Ningde, Fujian, China.
Kaiyuan ZhengDepartment of Joint Surgery and Sports Medicine, Ningde Municipal Hospital, Ningde, Fujian, China.
Wenrong ZhangDepartment of Orthopaedics, Pingnan County General Hospital, Ningde Municipal Hospital Medical Group, Pingnan, Fujian, China.
Shiqin ZhuoDepartment of Orthopaedics, Pingnan County General Hospital, Ningde Municipal Hospital Medical Group, Pingnan, Fujian, China.
Junli LiDepartment of Orthopaedics, Pingnan County General Hospital, Ningde Municipal Hospital Medical Group, Pingnan, Fujian, China.
Xiaoyong WangDepartment of Joint Surgery and Sports Medicine, Ningde Municipal Hospital, Ningde, Fujian, China.
Shuqiang LuDepartment of Orthopaedics, Pingnan County General Hospital, Ningde Municipal Hospital Medical Group, Pingnan, Fujian, China.
Jiuzao LinDepartment of Joint Surgery and Sports Medicine, Ningde Municipal Hospital, Ningde, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the feasibility of chondrogenic differentiation of rat adipose-derived stem cells (ADSCs) combined with sodium alginate (NaAlg) hydrogel scaffolds induced by cartilage-derived morphogenetic protein 1 (CDMP-1). Methods: ADSCs were isolated and cultured Results: Flow cytometry results showed that ADSCs were positive for surface antigens CD29, CD44 and CD105, and negative for CD31 and CD45. After chondrogenic induction, the cell proliferation curves of each group presented an approximate "S" shape, and there were statistically significant differences among all groups ( Conclusion: NaAlg hydrogel scaffold possesses favorable biosafety as a cell-carrier scaffold. CDMP-1 can effectively induce chondrogenic differentiation of ADSCs seeded on NaAlg hydrogel scaffolds

Indexed as

adipose-derived stem cellscartilage-derived morphogenetic protein-1chondrogenic differentiationsodium alginate hydrogelthree-dimensional culturetissue engineering

Identifiers

PMID42798657
PMCPMC13612550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.