ArticleFrontiers in sports and active living2026
Impact of a 2-year structured program on physical fitness and physical activity in T2D patients with rapid renal function decline-the ACTIDIANE RCT.
Article in Frontiers in sports and active living, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Long-term structured physical activity (PA) programs remain insufficiently evaluated in real-life settings for individuals living with type 2 diabetes (T2D). We assessed the effects of a 2-year high-intensity physical activity (HIPA) program on physical fitness and spontaneous PA. Methods: ACTIDIANE was a 21-center, open-label, randomized controlled trial comparing HIPA with standard PA recommendations (PAR) in 103 adults with T2D and rapid renal function decline. The HIPA intervention consisted of two supervised sessions per week delivered by certified adapted physical activity professionals over 24 months. Physical fitness and spontaneous PA were pre-specified secondary outcomes of the trial. Mixed models assessed group-by-time interactions over 24 months. Results: Baseline characteristics were similar between groups. Estimated Conclusions: In adults with T2D and rapid renal function decline, a 2-year structured HIPA program significantly improved estimated cardiorespiratory fitness, a clinically meaningful finding given the strong association between
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