Evidence map›Paper›PMID 42798428›Full record

ArticleFrontiers in endocrinology2026

Higher visceral fat area is inversely associated with ketosis in Chinese patients with type 2 diabetes mellitus: a cross-sectional study.

Jun-Wei Wang, Le Jiang, Jie Ren, Lin-Lin Gao, Ya-Nan Qiao, Shi-Wei Liu

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun-Wei Wang *Department of Endocrinology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, The Key Laboratory of Endocrine and Metabolic Diseases of Shanxi Province, Taiyuan, China.
Le Jiang *Department of Endocrinology, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China.
Jie Ren *Department of Orthopedics, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, China.
Lin-Lin GaoDepartment of Endocrinology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, The Key Laboratory of Endocrine and Metabolic Diseases of Shanxi Province, Taiyuan, China.
Ya-Nan QiaoDepartment of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, China.
Shi-Wei LiuDepartment of Endocrinology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, The Key Laboratory of Endocrine and Metabolic Diseases of Shanxi Province, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relationship between visceral fat area (VFA) and ketosis remains a subject of debate, with a paucity of research specifically addressing this association in individuals with type 2 diabetes mellitus (T2DM). This research seeks to investigate the connection between VFA and ketosis among Chinese patients diagnosed with T2DM. Methods: A cross-sectional study was performed, encompassing 1,058 patients with T2DM from real-world clinical environments. Body composition and visceral obesity were assessed through bioelectrical impedance analysis. The clinical characteristics of patients across varying quartiles of VFA were compared, and the relationships between VFA quartiles, visceral obesity, and ketosis were investigated. Results: After adjusting for age, gender and diabetes duration, ketosis prevalence appeared to gradually decrease across ascending VFA quartiles, with rates of 15.5%, 11.5%, 9.1% and 5.3% respectively, presenting a statistically significant trend (P < 0.001). Higher VFA categories tended to correlate with higher MASLD prevalence and elevated C-peptide levels (P < 0.001 for trend). Multivariate binary logistic regression indicated a potential inverse link between visceral obesity (OR = 0.409, 95%CI: 0.251-0.644, P<0.001), VFA quartile and ketosis occurrence among T2DM patients (P = 0.022 for trend). Conclusions: Higher visceral fat mass was associated with a lower prevalence of ketosis. Evaluation of visceral fat status can provide reference for personalized diet and medication management. Attention should be paid to ketosis in patients with low visceral fat.

Indexed as

Diabetes Mellitus, Type 2Intra-Abdominal FatKetosisObesity, AbdominalAdultAgedAsian PeopleBody CompositionChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceketosisMASLDtype 2 diabetes mellitusvisceral fat areavisceral obesity

Identifiers

PMID42798428
PMCPMC13612281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.