Evidence map›Paper›PMID 42798318›Full record

ArticleFrontiers in oral health2026

Intraoperative flap perfusion of radial free forearm flaps is associated with postoperative flap revision in microvascular head and neck reconstruction: a retrospective cohort study.

Mark Ooms, Philipp Winnand, Marius Heitzer, Nils Vohl, Marie Sophie Katz, Johannes Bickenbach, Frank Hölzle, Ali Modabber

Abstract read
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Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mark OomsDepartment of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Philipp WinnandDepartment of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Marius HeitzerDepartment of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Nils VohlDepartment of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Marie Sophie KatzDepartment of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Johannes BickenbachDepartment of Intensive Care Medicine, University Hospital RWTH Aachen, Aachen, Germany.
Frank HölzleDepartment of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Ali ModabberDepartment of Oral and Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative vascular flap compromise continues to occur in microvascular head and neck reconstruction, requiring time-consuming postoperative flap monitoring. This study assessed the association between intraoperative flap perfusion and postoperative flap revision. Methods: Flap perfusion measurement data collected intraoperatively with the Oxygen-2-see analysis system from 296 patients reconstructed with a radial free forearm flap in the head and neck region between 2011 and 2022 were retrospectively analyzed. Intraoperative flap blood flow, hemoglobin concentration, and hemoglobin oxygen saturation at 8 and 2 mm tissue depth were compared between patients without and with postoperative flap revision and cut-off values predicting postoperative flap revision were determined. Results: Intraoperative flap blood flow and hemoglobin oxygen saturation were lower and hemoglobin concentration was higher in patients with postoperative flap revision compared to patients without postoperative flap revision at 8 mm tissue depth [82.0 arbitrary units (AU) vs. 132.0 AU, Conclusions: Intraoperative flap perfusion was associated with postoperative flap revision, with cut-off values predicting postoperative flap revision determined as minimum blood flow and hemoglobin oxygen saturation and maximum hemoglobin concentration values. These findings should be confirmed in further studies to support the implementation of prevention strategies such as intraoperative anastomosis check and closer postoperative flap monitoring for flaps at risk.

Indexed as

blood flowflap perfusionflap revisionhemoglobin concentrationhemoglobin oxygen saturationmicrovascular head and neck reconstructionradial free forearm flaps

Identifiers

PMID42798318
PMCPMC13612183

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