Evidence map›Paper›PMID 42797584›Full record

ReviewVaccines2026

Knowledge, Attitudes, and Perceptions of HPV Vaccination for Adolescents with Intellectual Disabilities: A Systematic Review.

Giuseppina Lo Moro, Erica De Vita, Gianluca Voglino

Abstract readReview
In one paragraph

Review in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giuseppina Lo MoroDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-9472-3263
Erica De VitaDepartment of Translational Research and New Technologies in Medicine, University of Pisa, 56100 Pisa, Italy.ORCID 0000-0002-2659-0905
Gianluca VoglinoMinistry of Health, 00144 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesAdolescents with intellectual disabilities may experience inequities in preventive healthcare, including HPV vaccination. This review aimed to synthesize evidence on HPV vaccination-related knowledge, attitudes and perceptions among adolescents with intellectual disabilities, parents/caregivers, educators, healthcare professionals and other stakeholders.

methodsA systematic search was conducted in PubMed, Embase and Scopus on 29 October 2025. Eligible studies reported original data on knowledge, attitudes or perceptions regarding HPV vaccination for adolescents with intellectual disabilities or relevant stakeholders. The protocol was registered on PROSPERO (CRD420251015183). Quantitative, qualitative and mixed-methods studies were considered.

resultsSeven studies were included. They were conducted in the USA, Australia and the UK and involved parents/caregivers, healthcare providers, school staff, immunization staff and adolescents or young people with disabilities. Direct evidence from adolescents was limited. HPV-related knowledge was often limited or uneven, and standard information materials were perceived as insufficiently accessible. Parents/caregivers were often broadly supportive of vaccination, but HPV-specific acceptance was affected by perceived low susceptibility, assumptions about sexual inactivity, safety concerns, procedure-related distress and lack of provider recommendation. Healthcare providers generally supported HPV vaccination; however, recommendations were sometimes influenced by perceived sexual activity, age or consent. School-based vaccination was considered useful but required tailored information, preparation, individual adjustments and follow-up.

conclusionsEvidence on HPV vaccination-related knowledge, attitudes and perceptions among adolescents with intellectual disabilities and their stakeholders remains limited and geographically restricted. Improving equitable access may require interventions that should be further investigated, such as accessible communication, systematic provider recommendation, flexible vaccination pathways and greater involvement of adolescents in decision-making.

Indexed as

health knowledge, attitudes, practicehuman papillomavirusintellectual disability

Identifiers

PMID42797584
PMCPMC13611418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.