ArticlePharmaceuticals (Basel, Switzerland)2026
Fractional Factorial Design-Guided Optimization of Flavonoid Content and Antioxidant Capacity in
Waras Nurcholis, Gendhis Mahestri Handiani, I Made Artika, Syarifah Iis Aisyah, Gyath Karadsheh, Aditya Kurniawan, Viktória Poór, Tamás Marosvölgyi, Ulfa Elfiah, Endre Kristóf and 1 more
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Waras NurcholisDepartment of Biochemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor 16680, Indonesia.ORCID 0000-0001-7047-5093 Gendhis Mahestri HandianiDepartment of Biochemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor 16680, Indonesia.
I Made ArtikaDepartment of Biochemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor 16680, Indonesia.ORCID 0000-0003-4293-3389 Syarifah Iis AisyahTropical Biopharmaca Research Center, IPB University, Bogor 16128, Indonesia.
Gyath KaradshehDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0009-0004-6751-6834 Aditya KurniawanDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Viktória PoórInstitute of Bioanalysis, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Tamás MarosvölgyiInstitute of Bioanalysis, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0002-4244-5513 Ulfa ElfiahPlastic, Reconstructive and Aesthetic Surgery Division, Department of Surgery and Laboratory of Anatomy, Faculty of Medicine, University of Jember, Jember 68121, Indonesia.
Endre KristófDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-2215-6984 Rini AriantiDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-0525-4902 Funding
Hungarian Academy of SciencesIndonesia Endowment Fund for Education 42011/IT3/HK.07.00-4/P/B/2025Indonesia Endowment Fund for Education 4297/B3/DT.03.08/2025national research, development and innovation fund EKÖP-26-4-II-DE-4National Research, Development and Innovation Office FK145866National Research, Development and Innovation Office PD146202
6 · The paper itselfAbstract
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Indexed as
antioxidant capacityCUPRACDPPHextraction optimizationfractional factorial designFRAPJusticia gendarussametabolite profilingtotal flavonoid contentUHPLC-Q-Orbitrap HRMS
Identifiers
PMID42797511
PMCPMC13610638
What OpenQuestion holds
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