Evidence map›Paper›PMID 42797487›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Design, Synthesis, and Biological Evaluation of Novel ML-167 Analogues as Therapeutic Candidates Against Sarcopenia-Induced Muscle Wasting.

Issam Ameziane El Hassani, Shabnam Alizadeh, Sajda Ashraf, N Ceren Suer, Aybuke Ozturk, Woonghee Kim, Muhammed Melik Saracoglu, Edanur Yildiz, Seymanur Baycelebi, Gonca Candan and 12 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Issam Ameziane El HassaniTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.ORCID 0000-0002-3736-2545
Shabnam AlizadehTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.ORCID 0000-0003-3601-807X
Sajda AshrafTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.
N Ceren SuerTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.ORCID 0000-0002-6276-4124
Aybuke OzturkTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.
Woonghee KimScience for Life Laboratory, KTH-Royal Institute of Technology, SE-17165 Stockholm, Sweden.
Muhammed Melik SaracogluInstitute of Science, Atatürk University, Erzurum 25240, Türkiye.ORCID 0009-0009-3967-9878
Edanur YildizInstitute of Science, Atatürk University, Erzurum 25240, Türkiye.
Seymanur BaycelebiInstitute of Science, Erzurum Technical University, Erzurum 25240, Türkiye.
Gonca CandanTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.
Gizem Bati AyazTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.ORCID 0000-0002-8066-5867
Mustafa KaraTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.ORCID 0000-0002-6635-1589
Murat OzdemirTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.
Busra TuranTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.
Neaz AhmedTrustlife Labs, Drug Research & Development Center, Istanbul 34774, Türkiye.
Onur CeylanDepartment of Pathology, Faculty of Medicine, Atatürk University, Erzurum 25240, Türkiye.
Sevilay OzmenDepartment of Pathology, Faculty of Medicine, Atatürk University, Erzurum 25240, Türkiye.
Fatih IsikDepartment of Radiology, Faculty of Medicine, Atatürk University, Erzurum 25240, Türkiye.
Eda SahinDepartment of Radiology, Faculty of Medicine, Atatürk University, Erzurum 25240, Türkiye.
Fatih AlperDepartment of Radiology, Faculty of Medicine, Atatürk University, Erzurum 25240, Türkiye.ORCID 0000-0002-9483-8861
Hasan TurkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum 25240, Türkiye.ORCID 0000-0002-7046-8990
Adil MardinogluScience for Life Laboratory, KTH-Royal Institute of Technology, SE-17165 Stockholm, Sweden.ORCID 0000-0002-4254-6090

Funding

MOLİUS SAĞLIK TEKNOLOJİLERİ ANONİM ŞİRKETİ
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

in vivo rat modelmuscle atrophymyogenic differentiationmyogenin (MyoG)myosin heavy chain 3 (MyH3)preclinical efficacysarcopenia

Identifiers

PMID42797487
PMCPMC13610714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.