Evidence map›Paper›PMID 42797447›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Natural Small Molecules Targeting Mitochondrial Quality Control for the Treatment of Metabolic Diseases: Mechanisms, Novel Formulations, and Translational Perspectives.

Chongyan Zhao, Yuan Gao, Ting Zhou, Lei Sun, Qingsong Qu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chongyan ZhaoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102400, China.
Yuan GaoCollege of Traditional Chinese Medicine, Baotou Medical College, Baotou 014040, China.
Ting ZhouSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102400, China.
Lei SunSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102400, China.ORCID 0000-0002-0757-8476
Qingsong QuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102400, China.ORCID 0000-0002-0190-7187

Funding

Beijing University of Chinese Medicine 2025-JYB-JBGS-025Fundamental Research Funds for the Central Universities 2026-JYB-XJSJJ009National Natural Science Foundation of China (No. 82608371)
6 · The paper itself

Abstract

Metabolic diseases are jointly driven by insulin resistance, chronic inflammation, lipotoxicity, and disrupted organelle homeostasis arising from sustained nutrient overload. These disorders substantially increase the risk of cardiovascular, renal, and other multi-organ complications and have become a major global public health burden. Mitochondria are central organelles that integrate energy metabolism with stress signaling. They participate in fatty acid

Indexed as

metabolic diseasesmitochondriamitochondrial quality controlmitochondrial targeting strategynatural small molecules

Identifiers

PMID42797447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.