Evidence map›Paper›PMID 42797415›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Dopaminergic Radiopharmaceutical Imaging in Parkinsonian Syndromes: From Molecular Targets to Clinical Decision-Making.

Wael Jalloul, Cristina Mariana Uritu, Despina Jalloul, Vlad Ghizdovat, Andreia Vranceanu Ciobanu, Bogdan Ionel Tamba, Cipriana Stefanescu, Irena Cristina Grierosu

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wael JalloulDepartment of Biophysics and Medical Physics-Nuclear Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-5515-6473
Cristina Mariana UrituAdvanced Centre for Research and Development in Experimental Medicine "Prof. Ostin C. Mungiu", "Grigore T. Popa" University of Medicine and Pharmacy, 700259 Iasi, Romania.ORCID 0000-0002-7563-1267
Despina JalloulDepartment of Biophysics and Medical Physics-Nuclear Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Vlad GhizdovatDepartment of Biophysics and Medical Physics-Nuclear Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-8233-8862
Andreia Vranceanu CiobanuDepartment of Biophysics and Medical Physics-Nuclear Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Bogdan Ionel TambaAdvanced Centre for Research and Development in Experimental Medicine "Prof. Ostin C. Mungiu", "Grigore T. Popa" University of Medicine and Pharmacy, 700259 Iasi, Romania.ORCID 0000-0001-9868-1999
Cipriana StefanescuDepartment of Biophysics and Medical Physics-Nuclear Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-9697-750X
Irena Cristina GrierosuDepartment of Biophysics and Medical Physics-Nuclear Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-4881-5407

Funding

the Ministry of Education and Research, CCCDI-UEFISCDI project PN-IV-P6-6.1-CoEx-2024-0141, "Establishment of the Romanian Center of Excellence in Clinical Neuroscience (NeuRoX)", within PNCDI IV
6 · The paper itself

Abstract

Parkinsonian syndromes comprise overlapping neurodegenerative and non-degenerative disorders, making aetiological diagnosis difficult, while existing procedural guidance does not fully integrate tracer-specific biology with clinical decision-making, multimodal strategies, and emerging quantitative and pathology-directed biomarkers. This review synthesises evidence on the molecular targets, radiopharmaceutical characteristics, biological interpretation, and clinical applications of dopaminergic single-photon emission computed tomography (SPECT) and positron emission tomography (PET), focusing on the dopamine transporter (DAT), aromatic L-amino acid decarboxylase (AADC), vesicular monoamine transporter type 2 (VMAT2), dopamine D

Indexed as

[123I]ioflupane ([123I]FP-CIT)[18F]FDOPAartificial intelligencedopamine transporter (DAT)nigrostriatal dysfunctionparkinsonian syndromesParkinson’s diseasePETSPECTvesicular monoamine transporter type 2 (VMAT2)

Identifiers

PMID42797415
PMCPMC13610862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.