ReviewPolymers2026
Polymer-Based Biomaterials in Periodontal and Peri-Implant Soft Tissue Augmentation: Biological Rationale, Clinical Applications, and Future Perspectives.
Review in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soft tissue deficiencies around teeth and dental implants remain a significant challenge in contemporary periodontology and implant dentistry. These deficiencies influence a number of factors, including esthetic outcomes, peri-implant tissue stability, long-term maintenance, and patient satisfaction. Although autogenous connective tissue grafts remain the clinical gold standard for soft tissue augmentation, their use is limited by donor-site morbidity, increased surgical time, and restricted tissue availability. Consequently, polymer-based biomaterials have emerged as promising alternatives or adjunctive regenerative materials capable of improving wound healing while reducing surgical invasiveness. This narrative review compares natural polymers, including collagen, hyaluronic acid, extracellular matrix-derived scaffolds, fibrin-based platelet concentrates, and gelatin-based materials, with synthetic polymeric systems, such as polycaprolactone, polylactic acid, polyethylene glycol, and advanced composite hydrogels. The influence of these materials on angiogenesis, fibroblast migration, extracellular matrix remodeling, immune modulation, and soft tissue integration is reviewed in the context of periodontal plastic surgery and peri-implant soft tissue reconstruction. This narrative review summarizes the current landscape of polymer-based biomaterials used for periodontal and peri-implant soft tissue augmentation, integrating material science with clinical evidence. The advantages, limitations, indications and future perspectives of polymer-based substitutes are discussed in comparison with autogenous grafting procedures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.