Evidence map›Paper›PMID 42797162›Full record

ReviewPolymers2026

PVA Nanofibers by Solution Blow Spinning: Processing Principles, Challenges, and Biomedical Applications.

Fazila Ashraf, Dania Olmos, Javier González-Benito

Abstract readReview
In one paragraph

Review in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fazila AshrafMaterials Science and Engineering and Chemical Engineering, (IAAB) Universidad Carlos III de Madrid (UC3M), 28915 Leganes, Madrid, Spain.ORCID 0009-0005-3116-255X
Dania OlmosMaterials Science and Engineering and Chemical Engineering, (IAAB) Universidad Carlos III de Madrid (UC3M), 28915 Leganes, Madrid, Spain.ORCID 0000-0002-0419-301X
Javier González-BenitoMaterials Science and Engineering and Chemical Engineering, (IAAB) Universidad Carlos III de Madrid (UC3M), 28915 Leganes, Madrid, Spain.ORCID 0000-0002-8864-0971

Funding

Agencia Estatal de InvestigaciónAgencia Estatal de Investigación PID2023-147765OB-C21Spanish Ministry of Science, Innovation and Universities (MICIU)
6 · The paper itself

Abstract

Poly(vinyl alcohol) (PVA) nanofibers have emerged as versatile materials in biomedical science due to the high surface-to-volume ratio enabled by nanofibrous morphologies, together with their biocompatibility, hydrophilicity, low toxicity, water solubility, and ease of chemical modification. Solution blow spinning (SBS) provides an alternative route for producing PVA-based nanofibers and is particularly relevant for PVA because the polymer is commonly processed from aqueous solutions. This review critically examines the fabrication of PVA nanofibers by SBS within the broader framework established for PVA hydrogels and electrospun PVA nanofibers, emphasizing how aqueous processing conditions govern fiber formation and morphology and how these features translate into mechanical performance and functional behavior tailored to biomedical applications. Applications in wound dressings, drug-delivery systems, tissue engineering scaffolds, and biosensors are discussed, highlighting the role of the fillers/additives in modulating biological responses and drug release behavior. Key challenges remain, including water sensitivity and PVA solubility, crosslinking approaches compatible with bioactive payloads, and limitations in mechanical robustness for certain load-bearing applications. Finally, future perspectives on scale-up and eco-friendly PVA nanofibers are outlined to support translation of SBS-derived PVA nanofibers toward clinical applications. Overall, this work positions SBS as a promising route to complement established nanofiber fabrication methods and support the sustainable integration of PVA nanofibers into next-generation biomedical solutions, while providing broader insights into the processing of aqueous polymer systems by SBS.

Indexed as

biomedical applicationshydrogelsnanofibersnanoparticlespolyvinyl alcohol (PVA)solution blow spinning (SBS)

Identifiers

PMID42797162
PMCPMC13611765

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.