ArticlePolymers2026
From Carbohydrate to Biocompatible Carriers: Impact of Pegylation on the Physicochemical Properties and Quercetin Delivery Performance of Fructose Hydrothermal Carbons.
Article in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The aim of this study was to investigate the effect of PEG functionalization of hydrothermal carbon (HTC) on quercetin adsorption and desorption kinetics and, through that, evaluate the potential of functionalized HTC as a carrier for quercetin. Hydrothermal carbon (HTC) was synthesized using fructose as a precursor at a temperature of 160 °C. Structural and morphological analyses using X-ray diffraction and scanning electron microscopy (SEM) confirmed an amorphous carbon structure and microspherical particles with an average size of 5.6 µm. X-ray photoelectron spectroscopy (XPS) and Fourier Transform Infrared (FT-IR) spectroscopy characterization revealed a surface enriched with hydroxyl and carboxyl groups, which facilitated successful PEG modification. Surface modification was further corroborated by a zeta potential shift from -26.4 mV to -16.4 mV. Cytotoxicity assays in
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