Evidence map›Paper›PMID 42796990›Full record

ReviewNutrients2026

Dietary and Formulation Potential of Natural Oils and Fats in Ocular Health and Disease: Mechanisms, Evidence, and Future Directions.

Jiexin Bai, Xiangyi Fan, Youruo Zhang, Junguo Duan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiexin BaiEye Health with Traditional Chinese Medicine Key Laboratory of Sichuan Province, Retinal Image Technology and Chronic Vascular Disease Prevention & Control and Collaborative Innovation Center, Eye School of Chengdu University of TCM, Chengdu 610036, China.
Xiangyi FanEye Health with Traditional Chinese Medicine Key Laboratory of Sichuan Province, Retinal Image Technology and Chronic Vascular Disease Prevention & Control and Collaborative Innovation Center, Eye School of Chengdu University of TCM, Chengdu 610036, China.
Youruo ZhangEye Health with Traditional Chinese Medicine Key Laboratory of Sichuan Province, Retinal Image Technology and Chronic Vascular Disease Prevention & Control and Collaborative Innovation Center, Eye School of Chengdu University of TCM, Chengdu 610036, China.
Junguo DuanEye Health with Traditional Chinese Medicine Key Laboratory of Sichuan Province, Retinal Image Technology and Chronic Vascular Disease Prevention & Control and Collaborative Innovation Center, Eye School of Chengdu University of TCM, Chengdu 610036, China.

Funding

Noncommunicable Chronic Diseases-National Science and Technology Major Project 2023ZD0509300Sichuan Science and Technology 2023YFS0506
6 · The paper itself

Abstract

Natural oils and fats are multicomponent lipid matrices composed predominantly of triacylglycerols with source-specific fatty-acid profiles, together with variable amounts of phospholipids and minor lipophilic constituents. This narrative review discusses the nutritional, biological, and pharmaceutical relevance of oils from plant, terrestrial animal, and marine sources in ocular health and disease. Whole natural oils and fats are distinguished from isolated oil-associated constituents, multi-ingredient formulations, pharmaceutical oil phases or excipients, and engineered lipid-delivery systems. The discussion focuses on fatty acids, phospholipids, carotenoids, tocopherols, phytosterols, phenolic compounds, and other lipophilic constituents in relation to tear-film stability, epithelial homeostasis, inflammatory regulation, retinal function, and ophthalmic delivery. The available literature encompasses human studies, experimental models, cell-based research, and formulation studies. Human research is concentrated mainly on ocular-surface outcomes and product-specific interventions, whereas the literature concerning most intraocular and retinal conditions is derived predominantly from preclinical or mechanistic studies. The review also considers the influence of oil source, composition, extraction, refining, cooking, oxidation, formulation characteristics, administration route, and safety on the interpretation of oil-related ocular research.

Indexed as

EyeEye DiseasesOilsAnimalsHumansPlant OilsOilsPlant Oilsbioactive lipidsnatural oilsocular healthophthalmic formulationsoxidative stress

Identifiers

PMID42796990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.