Evidence map›Paper›PMID 42796952›Full record

Trial reportNutrients2026

Prenatal Folinic Acid in FRAA-Positive Pregnancies: Preschool Neurodevelopmental Outcomes from a Pilot RCT Follow-Up.

Claudio Giorlandino, Alvaro Mesoraca, Katia Margiotti, Marco Fabiani, Marina Cupellaro, Francesca Giorlandino, Maria Luisa Mastrandrea, Raffaella Raffio, Francesco Pignataro, Lucia Mangiafico and 3 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Claudio GiorlandinoHuman Genetics Lab, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.ORCID 0000-0002-8448-7260
Alvaro MesoracaHuman Genetics Lab, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Katia MargiottiHuman Genetics Lab, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.ORCID 0000-0003-0432-1525
Marco FabianiHuman Genetics Lab, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.ORCID 0000-0002-8763-0114
Marina CupellaroHuman Genetics Lab, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Francesca GiorlandinoHuman Genetics Lab, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Maria Luisa MastrandreaDepartment of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Raffaella RaffioDepartment of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Francesco PignataroDepartment of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Lucia MangiaficoDepartment of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Laura D'EmidioDepartment of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Claudio CocoDepartment of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
Vincenzo MiliteDepartment of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Autism Spectrum DisorderAutoantibodiesFolate Receptor 1LeucovorinPrenatal CareAdultChild, PreschoolFemaleFolic Acid DeficiencyFollow-Up StudiesHumansLongitudinal StudiesMaleNeurodevelopmentPilot ProjectsPregnancyAutoantibodiesFolate Receptor 1Leucovorinautism spectrum disordercerebral folate deficiencyfolate receptor alpha autoantibodiesfolinic acidprenatal supplementationpreschool neurodevelopment

Identifiers

PMID42796952
PMCPMC13610706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.