ArticleNutrients2026
Evaluation of the Intervention Effect of
Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesIt remains unclear whether sleep deprivation induces constipation. This study aimed to evaluate the intervention effects of
methodsA mouse model of sleep deprivation was established via the multiple platform water environment method. Through the detection and analysis of relevant indicators, the effects of sleep deprivation on intestinal function in mice were systematically investigated, and the changes in various indicators of mice after
resultsSleep deprivation significantly impaired intestinal motility and intestinal mucosal barrier function in mice, reducing fecal water content by approximately 21.4%, prolonging the time to first black stool defecation by about 57 min, and decreasing goblet cell count by nearly 50%. In terms of gastrointestinal hormones and neurotransmitters, sleep deprivation significantly downregulated the levels of excitatory gastrointestinal hormones (MTL, GAS) and excitatory neurotransmitter SP by 22.3%, 14.8%, and 16.2%, respectively. Additionally, sleep deprivation promoted the secretion of the inhibitory neurotransmitter VIP and stress hormone CORT, with their levels increased by 53.1% and 23.8%, respectively. The levels of neurotransmitters including 5HT and GABA were reduced by 15.6% and 23.2%, which ultimately led to a decrease in short-chain fatty acid (SCFA) levels. Intervention with
conclusions
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.