Evidence map›Paper›PMID 42796687›Full record

ReviewPathogens (Basel, Switzerland)2026

An Unexpected Limp: A Pediatric Case of Pott's Disease and a Literature Review.

Giulia Truglio, Giulia Linares, Gianluca Coscia, Valeria Garbo, Giovanni Boncori, Chiara Albano, Sara Ashtari, Alessandra Cuccia, Valentina Frasca Polara, Claudia Colomba

Abstract readCase ReportsReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulia TruglioDivision of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, Azienda di Rilievo Nazionale ad Alta Specializzazione (ARNAS) Civico, 90134 Palermo, Italy.ORCID 0009-0005-7631-6997
Giulia LinaresDivision of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, Azienda di Rilievo Nazionale ad Alta Specializzazione (ARNAS) Civico, 90134 Palermo, Italy.
Gianluca CosciaDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Valeria GarboDivision of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, Azienda di Rilievo Nazionale ad Alta Specializzazione (ARNAS) Civico, 90134 Palermo, Italy.
Giovanni BoncoriDivision of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, Azienda di Rilievo Nazionale ad Alta Specializzazione (ARNAS) Civico, 90134 Palermo, Italy.
Chiara AlbanoDivision of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, Azienda di Rilievo Nazionale ad Alta Specializzazione (ARNAS) Civico, 90134 Palermo, Italy.ORCID 0000-0003-4544-154X
Sara AshtariDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Alessandra CucciaDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.ORCID 0009-0002-9046-8944
Valentina Frasca PolaraDivision of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, Azienda di Rilievo Nazionale ad Alta Specializzazione (ARNAS) Civico, 90134 Palermo, Italy.
Claudia ColombaDivision of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, Azienda di Rilievo Nazionale ad Alta Specializzazione (ARNAS) Civico, 90134 Palermo, Italy.ORCID 0000-0003-3245-9396

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pott's disease, also known as tuberculous spondylodiscitis, accounts for 50% of all forms of skeletal tuberculosis. It is rare in children, especially in low-burden TB countries. We present a case of Pott's disease with miliary tuberculosis in a 22-month-old child. Furthermore, we provide an exploratory literature review of pediatric cases published in PubMed and Scopus between January 2000 and August 2025, including patients aged 0 to 17 years with confirmed or clinically diagnosed tuberculous spondylodiscitis. Sixty-four cases were included. Most cases (81.3%) involved children from highly endemic countries, particularly India. Median age was 10 years, with a median diagnostic delay of 141.4 days. The most common signs and symptoms were back pain (79.6%), followed by difficulty walking (68.4%). The thoracic spine was the most affected segment (60.3%). Sixty-three received anti-TB therapy, 58% required surgical intervention, and treatment led to overall clinical recovery in 96.9% of cases. Neurological deficits were reported in 46% (paresthesia) and 68.4% (motor weakness), with permanent motor sequelae in 8.1% and persistent spinal deformity (kyphosis) in 14.5%. Our case highlights the importance of considering the suspicion of tuberculous spondylodiscitis, even in low-endemic countries, to achieve early diagnosis and appropriate therapeutic management. Early MRI combined with microbiological confirmation is essential to reduce the risk of severe complications, including neurological sequelae, progressive spinal deformities, and potentially life-threatening outcomes in growing patients.

Indexed as

DiscitisTuberculosis, SpinalAdolescentAntitubercular AgentsChildChild, PreschoolFemaleHumansInfantMagnetic Resonance ImagingMaleAntitubercular Agentsantitubercular treatmentIRISMSMDMycobacterium tuberculosisparadoxical reactionpediatricpediatric tuberculosisPott’s diseasetuberculosistuberculous spondylodiscitis

Identifiers

PMID42796687
PMCPMC13610089

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.