Unusual Chemodivergence in the Amination of 2-Chloro-1,10-Phenanthroline with Di- and Polyamines: Comparison of the Pd-Catalyzed and Catalyst-Free Pathways.

Violetta A Ionova, Victoria E Gontcharenko, Konstantin S Viderskii, Alexei D Averin, Anton S Abel, Irina P Beletskaya

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Violetta A IonovaLomonosov Moscow State University, Department of Chemistry, 1-3, Leninskie Gory, Moscow 119991, Russia.ORCID 0000-0003-1193-0636

Victoria E GontcharenkoP.N. Lebedev Physical Institute of the Russian Academy of Sciences, 53, Leninsky Prospect, Moscow 119991, Russia.ORCID 0000-0001-6290-8880

Konstantin S ViderskiiLomonosov Moscow State University, Department of Chemistry, 1-3, Leninskie Gory, Moscow 119991, Russia.ORCID 0009-0007-1232-225X

Alexei D AverinLomonosov Moscow State University, Department of Chemistry, 1-3, Leninskie Gory, Moscow 119991, Russia.

Anton S AbelLomonosov Moscow State University, Department of Chemistry, 1-3, Leninskie Gory, Moscow 119991, Russia.ORCID 0000-0002-2951-4529

Irina P BeletskayaLomonosov Moscow State University, Department of Chemistry, 1-3, Leninskie Gory, Moscow 119991, Russia.ORCID 0000-0001-9705-1434

Funding

Ministry of Science and Higher Education 075-15-2024-547

6 · The paper itself

Abstract

The amination of 2-chloro-1,10-phenanthroline with various alkylamines and diamines was investigated. The Pd-catalyzed reaction and catalyst-free protocols were shown to lead to different products. Catalyst-free amination of this substrate using aliphatic amines yielded secondary phenanthrolin-2-yl amines in 40-80% yields. The Pd-catalyzed reaction afforded tertiary di(phenanthrolin-2-yl)amines even in the presence of excess amine. This allows for the synthesis of unsymmetric

Indexed as

1,10-phenanthrolineaminationdiaminesnucleophilic aromatic substitutionPd catalysis

Identifiers

PMID42796627

DOI10.3390/molecules31183344

PMCPMC13609841

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.