Evidence map›Paper›PMID 42796625›Full record

ReviewMolecules (Basel, Switzerland)2026

Pipitzols and Isopipitzols, 1852 to 2026: A Review.

Joel Martínez, Cristopher Williams Fuentes Cid, Adriana Lizbeth Rivera Espejel, María Inés Nicolás-Vázquez, María Z Saavedra-Leos, Alberto A Fajardo de la Rosa, René Gerardo Escobedo-González, René Miranda Ruvalcaba

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joel MartínezDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, Estado de México, Mexico.ORCID 0000-0002-6683-6738
Cristopher Williams Fuentes CidDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, Estado de México, Mexico.
Adriana Lizbeth Rivera EspejelDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, Estado de México, Mexico.ORCID 0000-0001-7951-1361
María Inés Nicolás-VázquezDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, Estado de México, Mexico.
María Z Saavedra-LeosCoordinación Académica Región Altiplano, Universidad Autónoma de San Luis Potosí, Carretera Cedral km 5+600, Ejido San José de las Trojes Matehuala 78700, San Luis Potosí, Mexico.ORCID 0000-0001-6721-7114
Alberto A Fajardo de la RosaLaboratorio de Ingeniería Química, Facultad de Química, Universidad Nacional Autónoma de México, Alcaldía Coyoacán, Ciudad de México 04510, Mexico.
René Gerardo Escobedo-GonzálezDepartment of Industrial Maintenance, Technological University of the City of Juárez, Av. Universidad Tecnológica No. 3051, Col. Lote Bravo II, City of Juárez 32315, Chihuahua, Mexico.ORCID 0000-0002-0640-0705
René Miranda RuvalcabaDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, Estado de México, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A thorough review of pipitzols and isopipitzols, covering the period 1852-2026, is presented. Perezone, the precursor of these compounds, is considered to be the first secondary metabolite isolated on the American continent, a phyto-molecule widely studied with regard to its spectra, chemical transformations, and especially its isolation and pharmacological activities. Perezone has several isomers: isoperezone, a synthetic molecule; and α- and β-pipitzols, two natural isomers of cedrenoid type achieved by thermal

Indexed as

computational chemistryisopipitzolspharmacological activitypipitzolsquantum chemistrytimeline

Identifiers

PMID42796625
PMCPMC13610303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.