Evidence map›Paper›PMID 42796513›Full record

ArticleMolecules (Basel, Switzerland)2026

4-Hydroxy-3-Methyl-2-Alkenylquinoline Disrupts Temporospatial Control of Flagellar Assembly and Induces Transcriptomic Remodeling in

McKinley D Williams, Leif Smith

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

McKinley D WilliamsDepartment of Biology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-8494-2315
Leif SmithDepartment of Biology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-0876-7260

Funding

Preclinical Development of OCF001 for Treatment of Yeast InfectionsR42AI131792 · NIAID · SANO CHEMICALS, INC · PI SMITH, JAMES LEIF · 2019 to 2021
$2.9M
Lead Compound Discovery from Engineered Analogs of OccidiofunginR41AI131792 · NIAID · SANO CHEMICALS, INC · PI SMITH, JAMES LEIF · 2017 to 2017
$225k
National Institute of Allergy and Infectious Diseases R41AI131792National Institute of Allergy and Infectious Diseases R42AI131792NIAID NIH HHS R41 AI131792NIAID NIH HHS R42 AI131792
6 · The paper itself

Abstract

4-hydroxy-3-methyl-2-alkenylquinolines (HMAQs) belong to an emerging sub-class of naturally synthesized alkaloids with several prominent biological properties. HMAQ-7 is a novel variant recently identified in

Indexed as

Bacillus subtilisBacterial ProteinsFlagellaQuinolinesTranscription FactorsTranscriptomeGene Expression Regulation, BacterialPhosphorylationBacterial ProteinsQuinolinesSpo0A protein, Bacillus subtilisTranscription Factorsalkaloidanti-biofilmantimicrobialanti-sporulationBacillus subtilisBurkholderiaflagellaquinoloneSpo0A

Identifiers

PMID42796513
PMCPMC13609334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.