ArticleMolecules (Basel, Switzerland)2026
Design, Synthesis, and Cytotoxic Evaluation of
Pablo S Cavagnero, Felipe A Zúñiga, Yaritza Ormazábal, Yeray A Rodríguez-Núñez, David Ramírez, Paulina V Hormazabal, Jorge Saavedra-Olavarría, Claudio A Jiménez, Efraín Polo-Cuadrado, Jhon J López
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Pablo S CavagneroDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción 4130000, Chile.ORCID 0009-0003-9437-0626 Felipe A ZúñigaDepartamento de Bioquímica Clínica e Inmunología, Facultad de Farmacia, Universidad de Concepción, Concepción 4130000, Chile.ORCID 0000-0003-0286-565X Yaritza OrmazábalDepartamento de Bioquímica Clínica e Inmunología, Facultad de Farmacia, Universidad de Concepción, Concepción 4130000, Chile.
Yeray A Rodríguez-NúñezLaboratorio de Síntesis y Reactividad de Compuestos Orgánicos, Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andrés Bello, Santiago 8370146, Chile.ORCID 0000-0003-4935-876X David RamírezDepartamento de Farmacología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción 4130000, Chile.ORCID 0000-0003-0002-1189 Paulina V HormazabalDepartamento de Farmacología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción 4130000, Chile.ORCID 0009-0008-6110-1573 Jorge Saavedra-OlavarríaDepartamento de Química Orgánica, Facultad de Química y de Farmacia, Escuela de Química, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0000-0002-2536-3065 Claudio A JiménezDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción 4130000, Chile.ORCID 0000-0002-2622-8308 Efraín Polo-CuadradoDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción 4130000, Chile.ORCID 0000-0003-2280-9321 Jhon J LópezDepartamento de Química Orgánica, Facultad de Química y de Farmacia, Escuela de Química, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0000-0002-2678-3627 Funding
the Programa de Inserción Académica 2026 of the Vicerrectoría Académica and Prorrectoría at Pontificia Univer-sidad Católica de Chile 1221631the Universidad de Concepción through internal research projects VRID No. 2023000895INT and VRID No. 2025001345INI
6 · The paper itselfAbstract
Indexed as
AcrylamideAcrylamidesAntineoplastic AgentsDrug DesignThiophenesCell Line, TumorCell SurvivalHumansMolecular StructureSpectroscopy, Fourier Transform InfraredStructure-Activity RelationshipAcrylamideAcrylamidesAntineoplastic AgentsThiophenesacrylamide derivativescytotoxicity assaydrug-like propertiesstructure–activity relationshipthiophene scaffold
Identifiers
PMID42796436
PMCPMC13609584
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