Evidence map›Paper›PMID 42796290›Full record

ReviewMedicina (Kaunas, Lithuania)2026

Anterior Cruciate Ligament Reconstruction: Clinical Outcomes and Biomechanical Considerations of Graft Selection-A Narrative Review.

Bogdan Huzum, Dan Viorel Cionca, Daniel Ciupilan, Cǎtǎlina Ionescu, Mihnea-Theodor Sîrbu, Malina Visternicu, Alin Ciobica, Oana Badulescu, Paul-Dan Sîrbu

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bogdan Huzum"Grigore T. Popa" University of Medicine and Pharmacy, University Street, No. 16, 700115 Iasi, Romania.
Dan Viorel Cionca"St. Spiridon" County Clinical Emergency Hospital, 700111 Iasi, Romania.
Daniel Ciupilan"St. Spiridon" County Clinical Emergency Hospital, 700111 Iasi, Romania.
Cǎtǎlina IonescuDoctoral School of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University of Iași, 700505 Iasi, Romania.ORCID 0009-0008-4979-1057
Mihnea-Theodor Sîrbu"Grigore T. Popa" University of Medicine and Pharmacy, University Street, No. 16, 700115 Iasi, Romania.ORCID 0009-0009-0891-1320
Malina VisternicuDoctoral School of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University of Iași, 700505 Iasi, Romania.
Alin CiobicaDepartment of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University of Iași, 700505 Iasi, Romania.
Oana Badulescu"Grigore T. Popa" University of Medicine and Pharmacy, University Street, No. 16, 700115 Iasi, Romania.ORCID 0000-0001-7050-8430
Paul-Dan Sîrbu"Grigore T. Popa" University of Medicine and Pharmacy, University Street, No. 16, 700115 Iasi, Romania.ORCID 0000-0003-2806-0649

Funding

Grigore T. Popa University of Medicine and Pharmacy 351058
6 · The paper itself

Abstract

Anterior cruciate ligament (ACL) reconstruction represents the current gold standard for restoring knee stability following ligament rupture, particularly in young and physically active individuals. The aim of this narrative review is to provide an updated overview of the biomechanical, biological, and clinical considerations underlying graft selection in ACL reconstruction, with particular emphasis on graft incorporation, fixation strategies, and postoperative outcomes. While surgical techniques and fixation devices have undergone substantial refinement, the optimal choice of graft remains a subject of ongoing debate. Traditionally, emphasis has been placed on the biomechanical characteristics of grafts, including tensile strength, stiffness, and resistance to cyclic loading. However, increasing attention has been directed toward biological factors that influence graft incorporation and clinical outcomes. The aim of this narrative review is to summarize the currently available literature regarding graft selection in ACL reconstruction by integrating biomechanical properties, biological graft incorporation, fixation strategies, and clinical outcomes. Particular emphasis is placed on the relationship between biomechanical performance and biological healing, as well as postoperative outcomes, in order to facilitate individualized graft selection in contemporary orthopedic practice.

Indexed as

Anterior Cruciate Ligament ReconstructionAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaHumansTreatment OutcomeACL reconstructionbiomechanicsclinical outcomesgraft failuregraft selectionreturn to sport

Identifiers

PMID42796290
PMCPMC13609259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.