Evidence map›Paper›PMID 42796075›Full record

ReviewJournal of clinical medicine2026

Reassessing the Role of Anthracyclines in Early HER2-Positive Breast Cancer in the Era of HER2-Targeted Therapy and Treatment De-Escalation: A Systematic Review and Narrative Synthesis.

Zhuldyz Myrzabay, Nazym Askambayeva, Ahmad J Harahsheh, Reezal Ishak, Mohamad Aljofan

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhuldyz MyrzabayDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, 5/1 Kerey and Zhanibek Khandar Str., 010000 Astana, Kazakhstan.
Nazym AskambayevaDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, 5/1 Kerey and Zhanibek Khandar Str., 010000 Astana, Kazakhstan.ORCID 0009-0004-3462-3609
Ahmad J HarahshehDepartment of Biology and Biotechnology, Faculty of Science, The Hashemite University, Zarqa 13133, Jordan.
Reezal IshakInstitute of Medical Science Technology (UniKL MESTECH), Universiti Kuala Lumpur, A1-1, Jalan TKS 1, Taman Kajang Sentral, Kajang 43000, Selangor, Malaysia.ORCID 0000-0001-7518-7365
Mohamad AljofanDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, 5/1 Kerey and Zhanibek Khandar Str., 010000 Astana, Kazakhstan.

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan AP26195341
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anthracycline-free regimenscardiotoxicityHER2-positive breast cancertrastuzumabtreatment de-escalation

Identifiers

PMID42796075
PMCPMC13607463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.