Evidence map›Paper›PMID 42795926›Full record

ArticleJournal of clinical medicine2026

The Patient-AI Relationship in Obsessive-Compulsive and Related Disorders: A Cognitive-Behavioral Framework.

Brian A Zaboski, Emmi Sugino, Kyle King

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brian A ZaboskiDepartment of Psychiatry, Yale School of Medicine, Yale University, New Haven, CT 06519, USA.ORCID 0000-0003-4567-8694
Emmi SuginoDepartment of Psychiatry, Yale School of Medicine, Yale University, New Haven, CT 06519, USA.
Kyle KingDepartment of Psychiatry, Yale School of Medicine, Yale University, New Haven, CT 06519, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generative artificial intelligence (AI) has evolved from a passive information tool into a responsive conversational system. For individuals with obsessive-compulsive and related disorders (OCRDs) that are, in part, maintained by safety behaviors and other negative reinforcement loops, large language models (LLMs) can function as highly available, potentially sycophantic, and readily repeatable sources of reassurance that may undermine the principles of exposure and response prevention (ERP). Measurement paradigms inherited from the early digital era (e.g., screen time and problematic internet use) were not designed to capture these relational dynamics. In this perspective, we propose a cognitive-behavioral framework for conceptualizing and assessing patient-AI relationships in the OCRDs. We argue that generative AI may interfere with exposure-based treatment (by eroding therapeutic friction), the discomfort, delay, and uncertainty on which corrective learning depends. We suggest that this occurs through three interlocking mechanisms: supernormal stimuli, algorithmic sycophancy, and digital accommodation. We propose an assessment architecture that records the context of AI use and rates five functional domains: Emotional Reliance, Reassurance and Checking, Anthropomorphic Attribution, Epistemic Trust, and Displacement. Adjunct ratings capture adaptive benefit, global interference, concealment, and safety-relevant exchanges. Hypothesized digital phenotypes may be derived from the domain-level profiles. We conclude by outlining a cognitive-behavioral approach to treatment planning for AI-facilitated reassurance seeking and discussing implications for safeguarding internal validity in research. We argue that structured inquiry into the patient-AI relationship belongs in OCRD assessment and research design, and we offer the present framework as a testable approach whose measurement properties remain to be established.

Indexed as

digital phenotypingexposure and response preventiongenerative artificial intelligencelarge language modelsobsessive–compulsive and related disordersreassurance seeking

Identifiers

PMID42795926
PMCPMC13607497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.