Evidence map›Paper›PMID 42795678›Full record

ArticleMicroorganisms2026

Multidrug-Resistant Bloodstream Infections Before and After COVID-19: A Temporal Assessment of Outcomes and Resistance Across Two Eras in a Non-COVID Intensive Care Unit-The MATURATE ICU Study.

Sotiria Kefala, Foteini Fligou, Ioannis Chandroulis, Marina Amerali, Stamatia Tsoupra, Eirini Zarkadi, Eleni Polyzou, Panagiota Pnevmatikou, Fevronia Kolonitsiou, Karolina Akinosoglou

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Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sotiria KefalaDepartment of Anesthesiology and Intensive Care, University General Hospital of Patras, 26504 Rio, Greece.
Foteini FligouDepartment of Anesthesiology and Intensive Care, University General Hospital of Patras, 26504 Rio, Greece.
Ioannis ChandroulisSchool of Science and Technology, Hellenic Open University, 26335 Patras, Greece.
Marina AmeraliDepartment of Anesthesiology and Intensive Care, University General Hospital of Patras, 26504 Rio, Greece.
Stamatia TsoupraDepartment of Anesthesiology and Intensive Care, University General Hospital of Patras, 26504 Rio, Greece.ORCID 0009-0004-0268-8854
Eirini ZarkadiDepartment of Anesthesiology and Intensive Care, University General Hospital of Patras, 26504 Rio, Greece.
Eleni PolyzouDepartment of Internal Medicine, University General Hospital of Patras, 26504 Rio, Greece.
Panagiota PnevmatikouDepartment of Microbiology, University General Hospital of Patras, 26504 Rio, Greece.
Fevronia KolonitsiouFaculty of Medicine, University of Patras, 26504 Rio, Greece.ORCID 0000-0002-4348-6077
Karolina AkinosoglouFaculty of Medicine, University of Patras, 26504 Rio, Greece.ORCID 0000-0002-4289-9494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic redirected infection control and antimicrobial stewardship towards SARS-CoV-2, potentially increasing multidrug-resistant (MDR) bloodstream infections (BSIs). We compared MDR BSI epidemiology and outcomes in a non-COVID intensive care unit (ICU) before and after the pandemic. The MATURATE ICU study retrospectively included adults with MDR BSIs admitted to a non-COVID ICU during the pre-COVID-19 (1 January 2017-1 January 2020) and post-COVID-19 (1 January 2022-1 January 2025) eras. Clinical, microbiological and outcome data were compared. Survival analyses and multivariable logistic regression identified predictors of ICU mortality. Overall, 146 patients were included (74 pre-COVID-19 and 72 post-COVID-19). Pre-COVID-19 patients were older and had higher comorbidity burden and severity indices (all

Indexed as

antimicrobial resistancebloodstream infectionsCOVID-19ICUmultidrug-resistant pathogens

Identifiers

PMID42795678
PMCPMC13609234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.