ArticleLife (Basel, Switzerland)2026
Feasibility of a SOFA-Derived Organ Dysfunction Score in Cats with Systemic Inflammatory Response Syndrome.
Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The Sequential Organ Failure Assessment (SOFA) score grades dysfunction in six components in people, using thresholds fixed against human reference ranges and a human case mix. Whether those numbers transfer to cats has not been examined. Of 52 cats assessed for eligibility, 23 met predefined systemic inflammatory response syndrome criteria, 22 of them non-septic, and an adapted score was calculated at admission from non-invasive measurements and one venous sample. A complete score was obtained in every cat. Under the applied bilirubin thresholds, the hepatic sub-score exceeded zero in 21 of 23 cats and, with the renal component, accounted for 63.0% of the mean total score; removing that component lowered the median total from 6.0 to 3.0 and left three cats scoring zero. Under stated physiological assumptions, translating the original PaO
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