Evidence map›Paper›PMID 42795332›Full record

ArticleLife (Basel, Switzerland)2026

Immunogenic Cell Death Induced by EEO in Breast Cancer Cells Promotes Dendritic Cell Activation in a CRT-Dependent Manner.

Seong-Ah Shin, Sun Young Moon, Seyeon Choi, Minji Kim, Moonsu Kim, Jun Hyuck Lee, Seulah Lee, Ki Hyun Kim, Hyun Ho Park, Ui Joung Youn and 1 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Seong-Ah ShinCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.
Sun Young MoonCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.
Seyeon ChoiCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.
Minji KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.
Moonsu KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.
Jun Hyuck LeeDepartment of Polar Sciences, University of Science and Technology, Incheon 21990, Republic of Korea.ORCID 0000-0002-4831-2228
Seulah LeeDepartment of Convergent Biotechnology and Advanced Materials Science, BK21 Interdisciplinary Program in IT-Bio Convergence System, Kyung Hee University, Yongin 17104, Republic of Korea.
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.ORCID 0000-0002-5285-9138
Hyun Ho ParkCollege of Pharmacy, Chung Ang University, Seoul 06974, Republic of Korea.ORCID 0000-0001-9928-0847
Ui Joung YounDepartment of Polar Sciences, University of Science and Technology, Incheon 21990, Republic of Korea.ORCID 0000-0001-9338-7934
Chang Sup LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.

Funding

Korea Polar Research Institute PE26220National Research Foundation of Korea RS-2025-25431554
6 · The paper itself

Abstract

Cancer immunotherapy faces significant challenges in treating "cold" tumors, which respond poorly to current strategies. Breast cancer is a major cause of cancer-related mortality in women and is a representative immunosuppressive cold tumor. The luminal A subtype of breast cancer exhibits an immune-cold phenotype, with MCF-7 cells used as a representative cell model. Here, we identified (3β,5α,8α)-5,8-epidioxyergost-6-en-3β-ol (EEO), isolated from

Indexed as

(3β,5α,8α)-5,8-epidioxyergost-6-en-3β-olbreast cancercalreticulincold tumordendritic cellimmunogenic cell deathmaturationphagocytosis

Identifiers

PMID42795332
PMCPMC13608123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.