Evidence map›Paper›PMID 42795011›Full record

ArticleCancers2026

Survival Impact of Bevacizumab According to Chemotherapy Response Score in Advanced High-Grade Serous Ovarian Carcinoma Treated with Neoadjuvant Chemotherapy.

Hasan Volkan Ege, Haticegul Tuncer, Utku Akgör, Murat Gultekin, Zafer Selcuk Tuncer, Derman Basaran

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hasan Volkan EgeDepartment of Gynecologic Oncology, Etlik City Hospital, Ankara 06170, Turkey.ORCID 0000-0002-4056-9037
Haticegul TuncerFaculty of Medicine, Department of Obstetrics and Gynecology, Hacettepe University, Ankara 06420, Turkey.
Utku AkgörFaculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynaecological Oncology, Hacettepe University, Ankara 06420, Turkey.ORCID 0000-0003-1377-2651
Murat GultekinFaculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynaecological Oncology, Hacettepe University, Ankara 06420, Turkey.ORCID 0000-0002-4221-4459
Zafer Selcuk TuncerFaculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynaecological Oncology, Hacettepe University, Ankara 06420, Turkey.
Derman BasaranFaculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynaecological Oncology, Hacettepe University, Ankara 06420, Turkey.ORCID 0000-0002-2689-1417

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChemotherapy response score (CRS) is a prognostic marker in high-grade serous ovarian carcinoma treated with neoadjuvant chemotherapy (NACT). This study evaluated whether the survival benefit associated with sustained bevacizumab exposure differs according to CRS group.

methodsWe retrospectively evaluated patients who underwent interval debulking surgery after platinum-taxane-based NACT between January 2015 and February 2025. Sustained bevacizumab exposure was defined as receipt of more than three cycles. Overall survival (OS) and OS after first recurrence (OS-FR) were assessed using Kaplan-Meier and Cox regression analyses.

resultsThe cohort included 113 patients: 30 with sustained bevacizumab exposure and 83 in the comparison group; 74 had CRS 1-2 and 39 had CRS 3. Sustained bevacizumab was associated with longer median OS in the overall cohort (57.4 vs. 50.3 months;

conclusionsSustained bevacizumab exposure was associated with longer OS and OS-FR, particularly in patients with CRS 1-2. CRS may help identify patients most likely to benefit from bevacizumab, although these findings require prospective validation.

Indexed as

bevacizumabchemotherapy response scoreovarian cancerrecurrent disease

Identifiers

PMID42795011
PMCPMC13605843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.