Evidence map›Paper›PMID 42794899›Full record

ArticleCancers2026

Discordant Antitumor Efficacy with Compromised Survival in High-Risk Unresectable Hepatocellular Carcinoma.

Young Eun Seo, Chan Joong Bae, Won Jae Lee, Sun Young Chun, Jun Sik Yoon, Yang-Hyun Baek, Yeo Wool Kang, Woo Sun Rou, Jeong Eun Song, Joonho Jeong and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Young Eun SeoDepartment of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.ORCID 0009-0009-8413-7306
Chan Joong BaeDepartment of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
Won Jae LeeDepartment of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
Sun Young ChunDepartment of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
Jun Sik YoonDepartment of Internal Medicine, School of Medicine, Keimyung University, Daegu 42601, Republic of Korea.ORCID 0000-0003-4328-3955
Yang-Hyun BaekDepartment of Internal Medicine, Dong-A University College of Medicine, Busan 49315, Republic of Korea.ORCID 0000-0002-9073-9233
Yeo Wool KangDepartment of Internal Medicine, Dong-A University College of Medicine, Busan 49315, Republic of Korea.
Woo Sun RouDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon 34134, Republic of Korea.ORCID 0000-0003-1619-2660
Jeong Eun SongDepartment of Internal Medicine, Daegu Catholic University Medical Center, School of Medicine, Catholic University of Daegu, Daegu 42472, Republic of Korea.ORCID 0000-0002-1034-4478
Joonho JeongDepartment of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Republic of Korea.
Young Mi HongDepartment of Internal Medicine, College of Medicine, Pusan National University Yangsan Hospital, Pusan National University, Yangsan 50615, Republic of Korea.
Sang Youn HwangDepartment of Internal Medicine, Dongnam Institute of Radiologic & Medical Sciences, Busan 46033, Republic of Korea.
Hyun Chin ChoDepartment of Internal Medicine, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52725, Republic of Korea.
Jung Pyo HongDepartment of Internal Medicine, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52725, Republic of Korea.
Hyun Young WooDepartment of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, College of Medicine, Pusan National University, Busan 49241, Republic of Korea.
Jeong HeoDepartment of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, College of Medicine, Pusan National University, Busan 49241, Republic of Korea.ORCID 0000-0003-0961-7851
Yu Rim LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, Daegu 41944, Republic of Korea.
Soo Young ParkDepartment of Internal Medicine, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, Daegu 41944, Republic of Korea.ORCID 0000-0002-4944-4396
Won Young TakDepartment of Internal Medicine, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, Daegu 41944, Republic of Korea.
Jae Hyun YoonDepartment of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.ORCID 0000-0002-4993-2496
Sung Bum ChoDepartment of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.

Funding

Chonnam National University 2025-0358-03
6 · The paper itself

Abstract

BACKGROUND/

objectivesReal-world data in high-risk patients remain limited; this study evaluated survival, safety, and prognostic factors in this patient group.

methodsThis multicenter study retrospectively reviewed 783 patients who received Ate/Bev from 2022-2024 across South Korea. High-risk patients (

resultsAfter PSM (251 pairs,

conclusionsAte/Bev achieved similar antitumor response rates in high-risk and non-high-risk patients, but survival remained poorer in the high-risk group. High-risk status therefore did not preclude antitumor activity with Ate/Bev.

Indexed as

atezolizumabbevacizumabduration of responsehepatocellular carcinomahigh-risk featurespropensity score

Identifiers

PMID42794899
PMCPMC13604502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.