Evidence map›Paper›PMID 42794887›Full record

ArticleCancers2026

LSD1 Promotes Immune Exclusion and Suppresses IFN-γ-Associated Transcriptional Programs in Triple-Negative Breast Cancer.

Dong Yeul Lee, Jing Han Hong, Peiyong Guan, Bernett Lee, Jianzhou Cui, Hui Xin Lau, Joe Poh Sheng Yeong, Puay Hoon Tan, Jinmiao Chen, Bin Tean Teh and 1 more

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dong Yeul LeeDepartment of Anatomical Pathology, Singapore General Hospital, Singapore 169856, Singapore.
Jing Han HongCancer and Stem Cell Biology Programme, Duke-NUS Graduate Medical School, Singapore 169857, Singapore.ORCID 0000-0002-2173-9192
Peiyong GuanNational Cancer Centre Singapore, Singapore 168583, Singapore.ORCID 0000-0001-9958-0137
Bernett LeeCentre of Biomedical Informatics, Nanyang Technological University, Singapore 636921, Singapore.ORCID 0000-0002-2709-1972
Jianzhou CuiImmunology Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.ORCID 0000-0003-1666-4082
Hui Xin LauDepartment of Anatomical Pathology, Singapore General Hospital, Singapore 169856, Singapore.
Joe Poh Sheng YeongDepartment of Anatomical Pathology, Singapore General Hospital, Singapore 169856, Singapore.
Puay Hoon TanLuma Medical Centre, Singapore 329565, Singapore.
Jinmiao ChenImmunology Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Bin Tean TehCancer and Stem Cell Biology Programme, Duke-NUS Graduate Medical School, Singapore 169857, Singapore.
Jabed IqbalDepartment of Anatomical Pathology, Singapore General Hospital, Singapore 169856, Singapore.ORCID 0000-0003-4137-1791

Funding

3rd A*STAR-AMed Joint Grant R23I2IR070Breast Diseases Research Fund 09/FY2024/EX/34-A86Kathy Goh Professorship 09/FY2024/DP(SL)/76-A163Khoo Postdoctoral Fellowship Award Duke-NUS-KPFA/ 2019/0034Moe Tier 1 FY2024-MOET1- 0002National Medical Research Council Open Fund-Individual Research Grant MOH-000144National Medical Research Council Open Fund-Individual Research Grant MOH-001890- 00National Medical Research Council Singapore Translational Research Investigator Award MOH-000248- 00 and MOH-001827- 00National Research Medical Council Singapore Young Individual Research Grant MOH-000232NCC Cancer FundSingapore Therapeutics Development Review Pre-Pilot H23G1a0009SingHealth Duke-NUS Genomic Medicine Centre Seed Grant DDC/FY2023/EX/79-A117Tan Yew Oo Professorship in Pathology 09/FY2023/DP(SL)/142-A197(a)Verdant Foundation
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

epigenetic therapyimmune exclusioninterferon-signaling-associated signatureLSD1/KDM1Apatient-derived organoidstriple-negative breast cancertumor microenvironment

Identifiers

PMID42794887
PMCPMC13604181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.