ArticleCancers2026
SBRT for Colorectal Cancer Liver Metastasis Is a Safe and Effective Treatment Option-A Single Institution Retrospective Analysis.
Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
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Abstract
backgroundColorectal cancer is the third most commonly diagnosed cancer in the world. Liver metastases are frequent, adversely affecting patient prognosis. We compared progression-free survival and overall survival in colorectal cancer patients with liver metastasis treated with surgical resection or stereotactic body radiotherapy. No previous study had shown superiority of one treatment option over the other.
methodsWe conducted a retrospective cohort study of 40 colorectal cancer patients with liver metastasis treated with surgical resection or stereotactic body radiotherapy at the Hebrew University-Hadassah Medical Center. Patient demographics, tumor characteristics, treatment details, and survival outcomes were analyzed. Kaplan-Meier curves and log-rank tests were used for survival analysis.
resultsThe median overall survival for the entire cohort was 44 months (95% CI 29-59 months). In patients treated with surgical resection, the median overall survival was 51 months (95% CI: 36-67 months), while in patients treated with stereotactic body radiotherapy the median overall survival was 32 months (95% CI: 21-43 months), a non-statistically significant result (
conclusionsOur findings underscore the importance of personalized treatment strategies tailored to the distinct characteristics of colorectal cancer patients with liver metastasis. Currently, surgical resection remains the standard of care. Further research is warranted to address the possibility of extending SBRT to first-line treatment in selected unresectable patients.
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