Evidence map›Paper›PMID 42794855›Full record

ArticleInternational journal of molecular sciences2026

Galectin-3 Mediates TGF-β-Controlled Migration in Müller Glial Cells.

Joshua Luis, Karen Eastlake, G Astrid Limb, Peng T Khaw, Hari Jayaram

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joshua LuisNational Institute for Health and Care Research Biomedical Research Centre for Ophthalmology, University College London Institute of Ophthalmology & Moorfields Eye Hospital, London EC1V 9EL, UK.ORCID 0000-0003-3621-1777
Karen EastlakeNational Institute for Health and Care Research Biomedical Research Centre for Ophthalmology, University College London Institute of Ophthalmology & Moorfields Eye Hospital, London EC1V 9EL, UK.
G Astrid LimbNational Institute for Health and Care Research Biomedical Research Centre for Ophthalmology, University College London Institute of Ophthalmology & Moorfields Eye Hospital, London EC1V 9EL, UK.ORCID 0000-0001-7014-8922
Peng T KhawNational Institute for Health and Care Research Biomedical Research Centre for Ophthalmology, University College London Institute of Ophthalmology & Moorfields Eye Hospital, London EC1V 9EL, UK.ORCID 0000-0002-8087-2268
Hari JayaramNational Institute for Health and Care Research Biomedical Research Centre for Ophthalmology, University College London Institute of Ophthalmology & Moorfields Eye Hospital, London EC1V 9EL, UK.

Funding

Academy of Medical Sciences SGL029\1027
6 · The paper itself

Abstract

Galectin-3 (Gal-3) is a ß-galactoside sugar-binding protein increasingly recognised for its role in systemic inflammation, fibrosis, and cancer. Within the retina, Müller glial cells (MGCs) are a major producer of Gal-3. This study aimed to investigate the impact of Gal-3 on the migration of MGCs. CRISPR-Cas9 knockout of Gal-3 resulted in slower cellular migration in MGCs (

Indexed as

Cell MovementEpendymoglial CellsGalectin 3Transforming Growth Factor betaAnimalsCell ProliferationCells, CulturedMiceGalectin 3Transforming Growth Factor betagalectingliosismigrationTGF-β

Identifiers

PMID42794855
PMCPMC13607565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.