Evidence map›Paper›PMID 42794825›Full record

ArticleInternational journal of molecular sciences2026

Evaluation of the Novaplex

Giuseppe Sberna, Francesca Colavita, Maria Beatrice Valli, Fabiano Brillo, Fabrizio Carletti, Silvia Meschi, Cosmina Mija, Claudia Minosse, Valentina Valeriani, Gabriella Rozera and 5 more

Abstract readEvaluation Study
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Giuseppe SbernaLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0003-0955-2074
Francesca ColavitaLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0003-0640-8667
Maria Beatrice ValliLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-5022-5388
Fabiano BrilloLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.
Fabrizio CarlettiLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0003-1952-5117
Silvia MeschiLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0003-0924-993X
Cosmina MijaLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.
Claudia MinosseLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-7833-9539
Valentina ValerianiLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.
Gabriella RozeraLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.
Giulia BernoLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0003-0331-2627
Flavia SmoquinaLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0009-0009-8975-0089
Lavinia FabeniLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0002-2975-8611
Fabrizio MaggiLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-7489-5271
Eleonora LalleLaboratory of Virology and Laboratories of Biosafety, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.

Funding

Ministero della Salute Programma Ricerca Corrente - Linea 1 on emerging and re-emerging infections
6 · The paper itself

Abstract

Arboviral infections represent a growing challenge for global public health due to vector expansion, globalization, and climate change. Dengue (DENV), Zika (ZIKV), Chikungunya (CHIKV), and West Nile virus (WNV) often co-circulate and present overlapping clinical manifestations, making rapid and accurate etiological diagnosis difficult. In this context, multiplex real-time RT-PCR assays can support clinical management and epidemiological surveillance. In this study, analytical and preliminary retrospective comparisons of the Novaplex

Indexed as

Multiplex Polymerase Chain ReactionChikungunya FeverChikungunya virusDengueDengue VirusHumansLimit of DetectionRetrospective StudiesRNA, ViralSensitivity and SpecificityWest Nile FeverWest Nile virusZika VirusRNA, ViralarbovirusesChikungunya virusCHIKVDengue virusDENVmultiplex PCRNovaplexWest Nile virusWNVZika virusZIKV

Identifiers

PMID42794825
PMCPMC13607916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.